[HTML][HTML] Cytoplasmic vacuolization in cell death and survival
Cytoplasmic vacuolization (also called cytoplasmic vacuolation) is a well-known
morphological phenomenon observed in mammalian cells after exposure to bacterial or viral …
morphological phenomenon observed in mammalian cells after exposure to bacterial or viral …
[PDF][PDF] Is genotype 3 of the hepatitis C virus the new villain?
Genotype 3 of the hepatitis C virus (HCV) has been long considered an easy‐to‐treat
infection, with higher cure rates (∼ 70%) than other viral genotypes with the standard …
infection, with higher cure rates (∼ 70%) than other viral genotypes with the standard …
Metabolic dysfunction-associated fatty liver disease and chronic viral hepatitis: the interlink
CJ Fernandez, M Alkhalifah, H Afsar, JM Pappachan - Pathogens, 2024 - mdpi.com
Metabolic dysfunction-associated fatty liver disease (MAFLD) has now affected nearly one-
third of the global population and has become the number one cause of chronic liver …
third of the global population and has become the number one cause of chronic liver …
Hepatitis C virus and lipid droplets: finding a niche
A Filipe, J McLauchlan - Trends in Molecular Medicine, 2015 - cell.com
Hepatitis C virus (HCV) causes serious liver disease in chronically infected individuals.
Infectious virions are released from hepatocytes as lipoprotein complexes, indicating that the …
Infectious virions are released from hepatocytes as lipoprotein complexes, indicating that the …
S100A11/ANXA2 belongs to a tumour suppressor/oncogene network deregulated early with steatosis and involved in inflammation and hepatocellular carcinoma …
C Sobolewski, D Abegg, F Berthou, D Dolicka, N Calo… - Gut, 2020 - gut.bmj.com
Objective Hepatocellular carcinoma (HCC) development occurs with non-alcoholic fatty liver
disease (NAFLD) in the absence of cirrhosis and with an increasing incidence due to the …
disease (NAFLD) in the absence of cirrhosis and with an increasing incidence due to the …
Dihydroartemisinin reduced lipid droplet deposition by YAP1 to promote the anti-PD-1 effect in hepatocellular carcinoma
L Hao, Y Guo, Q Peng, Z Zhang, J Ji, Y Liu, Y Xue, C Li… - Phytomedicine, 2022 - Elsevier
Background Anti-PD-1 was used to treat for many cancers, but the overall response rate of
monoclonal antibodies blocking the inhibitory PD-1/PD-L1 was less than 20%. Lipid droplet …
monoclonal antibodies blocking the inhibitory PD-1/PD-L1 was less than 20%. Lipid droplet …
[HTML][HTML] Pathogenesis and significance of hepatitis C virus steatosis: an update on survival strategy of a successful pathogen
Hepatitis C virus (HCV) is a successful pathogen on the grounds that it exploits its host's
metabolism to build up viral particles; moreover it favours its own survival by inducing …
metabolism to build up viral particles; moreover it favours its own survival by inducing …
Emerging role of lipid droplets in host/pathogen interactions
Lipid droplets (LDs) are highly dynamic cell organelles involved in energy homeostasis and
membrane trafficking. Here, we review how select pathogens interact with LDs. Several RNA …
membrane trafficking. Here, we review how select pathogens interact with LDs. Several RNA …
[HTML][HTML] Metabolic dysfunction and cancer in HCV: Shared pathways and mutual interactions
Hepatitis C virus hijacks many host metabolic processes in an effort to aid viral replication.
The resulting hepatic metabolic dysfunction underpins many of the hepatic and extrahepatic …
The resulting hepatic metabolic dysfunction underpins many of the hepatic and extrahepatic …
Lipid droplet formation in response to oleic acid in Huh-7 cells is mediated by the fatty acid receptor FFAR4
A Rohwedder, Q Zhang, SA Rudge… - Journal of cell …, 2014 - journals.biologists.com
It is unclear how changes in lipid droplet size and number are regulated–for example, it is
not known whether this involves a signalling pathway or is directed by cellular lipid uptake …
not known whether this involves a signalling pathway or is directed by cellular lipid uptake …