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[HTML][HTML] Improving immunovirotherapies: the intersection of mathematical modelling and experiments
CE Engeland, JPW Heidbuechel, RP Araujo… - ImmunoInformatics, 2022 - Elsevier
Combined oncolytic virotherapy and immunotherapy (immunovirotherapy) protocols
represent a promising treatment strategy for a range of cancers and offer many advantages …
represent a promising treatment strategy for a range of cancers and offer many advantages …
Distributed adaptive search in T cells: lessons from ants
There are striking similarities between the strategies ant colonies use to forage for food and
immune systems use to search for pathogens. Searchers (ants and cells) use the …
immune systems use to search for pathogens. Searchers (ants and cells) use the …
Oscillations in a spatial oncolytic virus model
AA Baabdulla, T Hillen - Bulletin of Mathematical Biology, 2024 - Springer
Virotherapy treatment is a new and promising target therapy that selectively attacks cancer
cells without harming normal cells. Mathematical models of oncolytic viruses have shown …
cells without harming normal cells. Mathematical models of oncolytic viruses have shown …
A tumor-immune interaction model for hepatocellular carcinoma based on measured lymphocyte counts in patients undergoing radiotherapy
Purpose The impact of radiation therapy on the immune system has recently gained
attention particularly when delivered in combination with immunotherapy. However, it is …
attention particularly when delivered in combination with immunotherapy. However, it is …
Tumour-associated macrophages and oncolytic virotherapies: a mathematical investigation into a complex dynamics
R Eftimie, G Eftimie - Letters in Biomathematics, 2018 - discovery.dundee.ac.uk
Anti-cancer therapies based on oncolytic viruses are emerging as important approaches in
cancer treatment. However, the effectiveness of these therapies depends significantly on the …
cancer treatment. However, the effectiveness of these therapies depends significantly on the …
Chaos and multistability behaviors in 4D dissipative cancer growth/decay model with unstable line of equilibria
The objective of this paper is to study the chaos and multistability behaviors in a 4D
dissipative chaotic cancer growth/decay model. The 4D chaotic cancer growth/decay model …
dissipative chaotic cancer growth/decay model. The 4D chaotic cancer growth/decay model …
[HTML][HTML] Mathematical modeling of oncolytic virus therapy reveals role of the immune response
E Guo, HM Dobrovolny - Viruses, 2023 - mdpi.com
Oncolytic adenoviruses (OAds) present a promising path for cancer treatment due to their
selectivity in infecting and lysing tumor cells and their ability to stimulate the immune …
selectivity in infecting and lysing tumor cells and their ability to stimulate the immune …
[HTML][HTML] A combination therapy of oncolytic viruses and chimeric antigen receptor T cells: a mathematical model proof-of-concept
Combining chimeric antigen receptor T (CAR-T) cells with oncolytic viruses (OVs) has
recently emerged as a promising treatment approach in preclinical studies that aim to …
recently emerged as a promising treatment approach in preclinical studies that aim to …
Stochastic dynamics of nonlinear tumor–immune system with chemotherapy
Motivated by important applications to the solution of the problem of studying the
mechanisms of tumor treatment, we consider a model of the dynamic interaction of tumor …
mechanisms of tumor treatment, we consider a model of the dynamic interaction of tumor …
Oncolytic viral therapies and the delicate balance between virus-macrophage-tumour interactions: A mathematical approach
The success of oncolytic virotherapies depends on the tumour microenvironment, which
contains a large number of infiltrating immune cells. In this theoretical study, we derive an …
contains a large number of infiltrating immune cells. In this theoretical study, we derive an …