The development of synthetic methods for the introduction of the fluorine atom and
fluoroalklyl groups into organic molecules has gained increased attention. Synthetic organic …

This review describes the recent advances made in difluoromethylation processes based on
X–CF2H bond formation where X is C (sp), C (sp2), C (sp3), O, N or S, a field of research …

Late-stage functionalization (LSF) introduces functional group or structural modification at
the final stage of the synthesis of natural products, drugs, and complex compounds. It is …

Aryl diazonium salts are versatile building blocks in organic synthesis. In light of the ever-
increasing importance of aryl diazonium salts spanning most disciplines of the chemical …

Owing to the excellent performance of fluorinated compounds in the areas of
pharmaceuticals, agrochemicals, and materials chemistry, organic chemists have made …

Currently, the chemistry of organofluorine compounds is a leading and rapidly develo**
area of organic chemistry. Fluorine present in a molecule largely determines its specific …

Herein, we report a convenient and broadly applicable strategy for the difluoromethylation of
aryl bromides by metallaphotoredox catalysis. Bromodifluoromethane, a simple and …

Abstract A nickel‐catalyzed 1, 4‐carbofluoroalkylation of 1, 3‐enynes to access structurally
diverse fluoroalkylated allenes has been established. This method has demonstrated high …

Fluoroalkyl fragments have played a critical role in the design of pharmaceutical and
agrochemical molecules in recent years due to the enhanced biological properties of …

Given their ubiquity in natural products and pharmaceuticals, alcohols represent one of the
most attractive starting materials for the construction of C–C bonds. We report herein the first …