[HTML][HTML] The aryl hydrocarbon receptor as a target of environmental stressors–Implications for pollution mediated stress and inflammatory responses

CFA Vogel, LS Van Winkle, C Esser… - Redox biology, 2020 - Elsevier
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor regulating the
expression of genes, for instance encoding the monooxygenases cytochrome P450 (CYP) …

A comprehensive understanding of ambient particulate matter and its components on the adverse health effects based from epidemiological and laboratory evidence

T Li, Y Yu, Z Sun, J Duan - Particle and fibre toxicology, 2022 - Springer
The impacts of air pollution on public health have become a great concern worldwide.
Ambient particulate matter (PM) is a major air pollution that comprises a heterogeneous …

NOX dependent ROS generation and cell metabolism

T Pecchillo Cimmino, R Ammendola… - International Journal of …, 2023 - mdpi.com
Reactive oxygen species (ROS) represent a group of high reactive molecules with dualistic
natures since they can induce cytotoxicity or regulate cellular physiology. Among the ROS …

Environmental stressors on skin aging. Mechanistic insights

C Parrado, S Mercado-Saenz, A Perez-Davo… - Frontiers in …, 2019 - frontiersin.org
The skin is the main barrier that protects us against environmental stressors (physical,
chemical, and biological). These stressors, combined with internal factors, are responsible …

Impact of airborne particulate matter on skin: A systematic review from epidemiology to in vitro studies

IM Dijkhoff, B Drasler, BB Karakocak… - Particle and fibre …, 2020 - Springer
Background Air pollution is killing close to 5 million people a year, and harming billions
more. Air pollution levels remain extremely high in many parts of the world, and air pollution …

Impact of air pollution on atopic dermatitis: a comprehensive review

Z Pan, Y Dai, N Akar-Ghibril, J Simpson, H Ren… - Clinical Reviews in …, 2023 - Springer
Air pollution is associated with multiple health problems worldwide, contributing to increased
morbidity and mortality. Atopic dermatitis (AD) is a common allergic disease, and increasing …

Aryl hydrocarbon receptor in oxidative stress as a double agent and its biological and therapeutic significance

AY Grishanova, ML Perepechaeva - International Journal of Molecular …, 2022 - mdpi.com
The aryl hydrocarbon receptor (AhR) has long been implicated in the induction of a battery
of genes involved in the metabolism of xenobiotics and endogenous compounds. AhR is a …

The role of reactive oxygen species in the biological activity of antimicrobial agents: An updated mini review

PL Lam, RSM Wong, KH Lam, LK Hung… - Chemico-Biological …, 2020 - Elsevier
Antimicrobial resistance remains a serious problem that results in high mortality and
increased healthcare costs globally. One of the major issues is that resistant pathogens …

miR-590-3p inhibits pyroptosis in diabetic retinopathy by targeting NLRP1 and inactivating the NOX4 signaling pathway

C Gu, D Draga, C Zhou, T Su, C Zou… - … & visual science, 2019 - iovs.arvojournals.org
Purpose: To elucidate the mechanism whereby miR-590-3p regulates pyroptosis in diabetic
retinopathy (DR). Methods: Human retinal microvascular endothelial cells (HRMECs) …

Can plant phenolic compounds protect the skin from airborne particulate matter?

YC Boo - Antioxidants, 2019 - mdpi.com
The skin is directly exposed to the polluted atmospheric environment, and skin diseases,
such as atopic dermatitis and acne vulgaris, can be induced or exacerbated by airborne …