Neutrophil recruitment and function in health and inflammation
Neutrophils have traditionally been thought of as simple foot soldiers of the innate immune
system with a restricted set of pro-inflammatory functions. More recently, it has become …
system with a restricted set of pro-inflammatory functions. More recently, it has become …
Neutrophils as emerging therapeutic targets
Neutrophils are the most abundant circulating leukocytes, being the first line of defence
against bacterial and fungal infections. However, neutrophils also contribute to tissue …
against bacterial and fungal infections. However, neutrophils also contribute to tissue …
[HTML][HTML] An immune-based biomarker signature is associated with mortality in COVID-19 patients
Immune and inflammatory responses to severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) contribute to disease severity of coronavirus disease 2019 (COVID-19) …
(SARS-CoV-2) contribute to disease severity of coronavirus disease 2019 (COVID-19) …
Neutrophils in COVID-19
Strong evidence has been accumulated since the beginning of the COVID-19 pandemic that
neutrophils play an important role in the pathophysiology, particularly in those with severe …
neutrophils play an important role in the pathophysiology, particularly in those with severe …
A neutrophil activation signature predicts critical illness and mortality in COVID-19
Pathologic immune hyperactivation is emerging as a key feature of critical illness in COVID-
19, but the mechanisms involved remain poorly understood. We carried out proteomic …
19, but the mechanisms involved remain poorly understood. We carried out proteomic …
[HTML][HTML] Neutrophil extracellular traps mediate m6A modification and regulates sepsis-associated acute lung injury by activating ferroptosis in alveolar epithelial cells
H Zhang, J Liu, Y Zhou, M Qu, Y Wang… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Neutrophil extracellular traps (NETs) production is a major strategy employed by
polymorphonuclear neutrophils (PMNs) to fight against microbes. NETs have been …
polymorphonuclear neutrophils (PMNs) to fight against microbes. NETs have been …
DAMPs and NETs in sepsis
Sepsis is a deadly inflammatory syndrome caused by an exaggerated immune response to
infection. Much has been focused on host response to pathogens mediated through the …
infection. Much has been focused on host response to pathogens mediated through the …
[HTML][HTML] The potential impact of zinc supplementation on COVID-19 pathogenesis
I Wessels, B Rolles, L Rink - Frontiers in immunology, 2020 - frontiersin.org
During the current corona pandemic, new therapeutic options against this viral disease are
urgently desired. Due to the rapid spread and immense number of affected individuals …
urgently desired. Due to the rapid spread and immense number of affected individuals …
[HTML][HTML] Devilishly radical NETwork in COVID-19: Oxidative stress, neutrophil extracellular traps (NETs), and T cell suppression
G Schönrich, MJ Raftery, Y Samstag - Advances in biological regulation, 2020 - Elsevier
Abstract Pandemic coronavirus disease 2019 (COVID-19) is caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) and poses an unprecedented challenge …
respiratory syndrome coronavirus 2 (SARS-CoV-2) and poses an unprecedented challenge …
Innate immune responses to trauma
Trauma can affect any individual at any location and at any time over a lifespan. The
disruption of macrobarriers and microbarriers induces instant activation of innate immunity …
disruption of macrobarriers and microbarriers induces instant activation of innate immunity …