Coprescribing proton-pump inhibitors with nonsteroidal anti-inflammatory drugs: risks versus benefits

KA Gwee, V Goh, G Lima, S Setia - Journal of pain research, 2018 - Taylor & Francis
Nonsteroidal anti-inflammatory drugs (NSAIDs) are often coadministered with proton-pump
inhibitors (PPIs) to reduce NSAID-induced gastrointestinal (GI) adverse events. This …

[HTML][HTML] Small bowel capsule endoscopy: Where are we after almost 15 years of use?

C Van de Bruaene, D De Looze… - World journal of …, 2015 - ncbi.nlm.nih.gov
The development of capsule endoscopy (CE) in 2001 has given gastroenterologists the
opportunity to investigate the small bowel in a non-invasive way. CE is most commonly …

The microbiota-derived metabolite indole decreases mucosal inflammation and injury in a murine model of NSAID enteropathy

CM Whitfield-Cargile, ND Cohen, RS Chapkin… - Gut …, 2016 - Taylor & Francis
Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most frequently used classes
of medications in the world. Unfortunately, NSAIDs induce an enteropathy associated with …

Adipose-derived stem cell exosomes as a novel anti-inflammatory agent and the current therapeutic targets for rheumatoid arthritis

TH Chang, CS Wu, SH Chiou, CH Chang, HJ Liao - Biomedicines, 2022 - mdpi.com
Patients with rheumatoid arthritis (RA), a chronic inflammatory joint disorder, may not
respond adequately to current RA treatments. Mesenchymal stem cells (MSCs) elicit several …

Nonsteroidal anti-inflammatory drugs, proton pump inhibitors, and gastrointestinal injury: contrasting interactions in the stomach and small intestine

W Marlicz, I Łoniewski, DS Grimes, EM Quigley - Mayo Clinic Proceedings, 2014 - Elsevier
Nonsteroidal anti-inflammatory drugs (NSAIDs) and proton pump inhibitors (PPIs) are
among the most frequently prescribed groups of drugs worldwide. The use of NSAIDs is …

Prominent Indomethacin-Induced Enteropathy in Fcgriib Defi-cient lupus Mice: An Impact of Macrophage Responses and Immune Deposition in Gut

T Bhunyakarnjanarat, K Udompornpitak… - International journal of …, 2021 - mdpi.com
A high dose of NSAIDs, a common analgesic, might induce lupus activity through several
NSAIDs adverse effects including gastrointestinal permeability defect (gut leakage) and …

Controlled release of optimized electroporation enhances the transdermal efficiency of sinomenine hydrochloride for treating arthritis in vitro and in clinic

S Feng, L Zhu, Z Huang, H Wang, H Li… - Drug design …, 2017 - Taylor & Francis
Sinomenine hydrochloride (SH) is an ideal drug for the treatment of rheumatoid arthritis and
osteoarthritis. However, high plasma concentration of systemically administered SH can …

a practical approach to the clinical management of NSAID enteropathy

A Srinivasan, P De Cruz - Scandinavian journal of gastroenterology, 2017 - Taylor & Francis
Co-prescription of acid suppressive therapy, together with advances in small bowel imaging
techniques, have shifted the burden of NSAID-related toxicity from gastro-duodenal to more …

NSAID enteropathy: appearance at CT and MR enterography in the age of multi-modality imaging and treatment

JM Frye, SL Hansel, SG Dolan, JL Fidler… - Abdominal …, 2015 - Springer
CT and MR enterography and capsule endoscopy are increasingly used as routine
diagnostic tests for patients with potential small bowel disorders and obscure …

Small intestinal injury in NSAID users suffering from rheumatoid arthritis or osteoarthritis

I Tachecí, P Bradna, T Douda, D Baštecká… - Rheumatology …, 2016 - Springer
The goal of this prospective study was to assess non-steroidal anti-inflammatory drug
(NSAID)-induced enteropathy in patients with rheumatoid arthritis (RA) or osteoarthritis (OA) …