Epilepsy is a common and serious neurologic disease with a strong genetic component.
Genetic studies have identified an increasing collection of disease-causing genes. The …

A number of mutations to members of several CNS potassium (K) channel families have
been identified which result in rare forms of neonatal onset epilepsy, or syndromes of which …

With the development and application of next‐generation sequencing technology, the
aetiological diagnosis of genetic epilepsy is rapidly becoming easier and less expensive …

Potassium channels play an important role in human physiological function. Recently,
various molecular mechanisms have implicated abnormal functioning of potassium …

The field of mitochondrial ion channels has undergone a rapid development during the last
three decades, due to the molecular identification of some of the channels residing in the …

Nanosecond pulsed electric fields (nsPEFs) have a variety of applications in the biomedical
and biotechnology industries. Cancer treatment has been at the forefront of investigations …

Microglial phagocytosis benefits neurological recovery after stroke. Large-conductance
Ca2+-activated K+ currents are expressed in activated microglia, and BK channel knockout …

This review categorizes functionally validated actions of defined scorpion toxin (SCTX)
neuropeptides across ion channel subclasses, highlighting key trends in this rapidly …

Habituation is a basic form of implicit learning and represents a sensory filter that is
disrupted in autism, schizophrenia, and several other mental disorders. Despite extensive …

The activation of mitochondrial calcium-sensitive potassium (mBKCa) channels is crucially
involved in cardioprotection induced by preconditioning. For milrinone (Mil)-induced …