Synthesis and anticancer activities of novel 1, 2, 4-triazolo [3, 4-a] phthalazine derivatives

DQ Xue, XY Zhang, CJ Wang, LY Ma, N Zhu… - European Journal of …, 2014 - Elsevier
Trying to develop potent and selective anticancer agents, two series of novel 1, 2, 4-triazolo
[3, 4-a] phthalazine derivatives were designed and synthesized. Their antitumor activities …

Synthesis and antimicrobial activities of novel 1, 2, 4-triazolo [3, 4-a] phthalazine derivatives

QR Zhang, DQ Xue, P He, KP Shao, PJ Chen… - Bioorganic & medicinal …, 2014 - Elsevier
Abstract A series of novel 1, 2, 4-triazolo [3, 4-a] phthalazine derivatives were synthesized in
five steps from a common precursor, phthalic anhydride. Most of synthesized phthalazine …

Synthesis and antimicrobial activity of some annelated quinazoline derivatives

AA Aly - Journal of the Chinese Chemical Society, 2007 - Wiley Online Library
A highly efficient and versatile synthetic approach to the synthesis of annelated quinazoline
derivatives viz 1, 2, 4‐triazino [4, 3‐c] quinazoline 5–7, 11, thiazolidinylquinazoline 9 …

Polyphosphoric acid (PPA): a new, highly efficient catalyst for the synthesis of functionalized azepino phthalazine hybrids

E Lamera, A Chibani, Z Bouaziz, ML Borgne… - … für Naturforschung B, 2024 - degruyter.com
A new, convenient and efficient method for the construction of a new polycyclic condensed
system containing an azepine and pyrazolophthalazine has been developed in the form of a …

Synthesis and antimicrobial activity of some annelated quinazoline derivatives

AA Aly - Zeitschrift für Naturforschung B, 2006 - degruyter.com
A highly efficient and versatile synthetic approach to the synthesis of annelated quinazoline
derivatives viz. 3, 4, 9, 10a-tetraazaphenanthrenes 5-7, thiazolidinylquinazoline 9, 2, 4, 9 …

A Convenient Synthesis of Novel Functionalized Pyrimido [5′, 4′: 4, 5] thieno [3, 2-c] pyridazines and Related Fused Systems

AA Aly - Phosphorus, Sulfur, and Silicon, 2008 - Taylor & Francis
Possible approaches to the synthesis of functionalized, pyrimido [5′, 4′: 4, 5] thieno [3, 2-
c] pyridazines 2-18, pyridazino [3′, 4′: 4, 5] thieno [2, 3-d] triazines 19, 20a, b and pyrido …

Synthesis and Antitumor Activity Evaluation of 3, 6-Substituted-1, 2, 4-triazolo [3, 4-a] phthalazine Derivatives

C Wang, Q Cao, H Yang, P Song, D Xue… - Chinese Journal of …, 2016 - sioc-journal.cn
With the aim of obtaining potential antitumor candidates with more efficiency and more
economic value. A series of 3, 6-substituted-1, 2, 4-triazolo [3, 4-a] phthalazine derivatives …

3, 6-取代-1, 2, 4-三氮唑 [3, 4-a] 酞嗪衍生物的合成和抗肿瘤活性评价

王超杰, 曹钦坡, 杨慧, 宋攀攀, 薛登启, 崔飞, 顾一飞… - 有机化学, 2016 - sioc-journal.cn
摘要为了寻找高效, 经济的抗肿瘤药物, 以邻苯二甲酸酐为起始原料, 经环合, 氯代,
取代和环合等反应, 合成一系列的3, 6-取代-1, 2, 4-三氮唑并[3, 4-a] 酞嗪衍生物 …

[CITATION][C] Bicyclic 6-6 Systems With One Bridgehead (Ring Junction) Nitrogen Atom: Three Extra Heteroatoms (2: 1)

OO Grygorenko, V Hutskalova, VS Moskvina - 2022 - Elsevier