Plants metabolites: possibility of natural therapeutics against the COVID-19 pandemic

FR Bhuiyan, S Howlader, T Raihan, M Hasan - Frontiers in medicine, 2020 - frontiersin.org
COVID-19, a disease induced by SARS-CoV-2 (Severe Acute Respiratory Syndrome
Coronavirus-2), has been the cause of a worldwide pandemic. Though extensive research …

[HTML][HTML] Review of evidence available on hesperidin-rich products as potential tools against COVID-19 and hydrodynamic cavitation-based extraction as a method of …

F Meneguzzo, R Ciriminna, F Zabini, M Pagliaro - Processes, 2020 - mdpi.com
Based on recent computational and experimental studies, hesperidin, a bioactive flavonoid
abundant in citrus peel, stands out for its high binding affinity to the main cellular receptors of …

Natural flavonoids as potential angiotensin-converting enzyme 2 inhibitors for anti-SARS-CoV-2

M Muchtaridi, M Fauzi, NK Khairul Ikram… - Molecules, 2020 - mdpi.com
Over the years, coronaviruses (CoV) have posed a severe public health threat, causing an
increase in mortality and morbidity rates throughout the world. The recent outbreak of a …

Molecular basis of SARS-CoV-2 infection and rational design of potential antiviral agents: modeling and simulation approaches

A Frances-Monerris, C Hognon, T Miclot… - Journal of Proteome …, 2020 - ACS Publications
The emergence in late 2019 of the coronavirus SARS-CoV-2 has resulted in the
breakthrough of the COVID-19 pandemic that is presently affecting a growing number of …

Methodology-centered review of molecular modeling, simulation, and prediction of SARS-CoV-2

K Gao, R Wang, J Chen, L Cheng, J Frishcosy… - Chemical …, 2022 - ACS Publications
Despite tremendous efforts in the past two years, our understanding of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), virus–host interactions, immune …

[HTML][HTML] In silico evaluation of natural flavonoids as a potential inhibitor of coronavirus disease

P Kashyap, M Thakur, N Singh, D Shikha, S Kumar… - Molecules, 2022 - mdpi.com
The recent coronavirus disease (COVID-19) outbreak in Wuhan, China, has led to millions of
infections and the death of approximately one million people. No targeted therapeutics are …

Repurposing drugs and identification of inhibitors of integral proteins (spike protein and main protease) of SARS-CoV-2

FO Shode, ASK Idowu, OJ Uhomoibhi… - Journal of Biomolecular …, 2022 - Taylor & Francis
The outbreak of Coronavirus infection (COVID-19) has prompted the World Health
Organisation (WHO) to declare the outbreak, a Public Health Emergency of International …

Multi-omics approach in the identification of potential therapeutic biomolecule for COVID-19

R Singh, PK Singh, R Kumar, MT Kabir… - Frontiers in …, 2021 - frontiersin.org
COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It
has a disastrous effect on mankind due to the contagious and rapid nature of its spread …

[HTML][HTML] Current updates on naturally occurring compounds recognizing SARS-CoV-2 druggable targets

I Romeo, F Mesiti, A Lupia, S Alcaro - Molecules, 2021 - mdpi.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been identified in
China as the etiologic agent of the recent COVID-19 pandemic outbreak. Due to its high …

Inhibitory mechanism of clioquinol and its derivatives at the exopeptidase site of human angiotensin-converting enzyme-2 and receptor binding domain of SARS-CoV …

IA Kehinde, A Egbeyemi, M Kaur… - Journal of …, 2023 - Taylor & Francis
The outbreak of SARS-CoV-2 infections around the world has prompted scientists to explore
different approaches to develop therapeutics against COVID-19. This study focused on …