Intrinsically disordered regions are poised to act as sensors of cellular chemistry
Intrinsically disordered proteins and protein regions (IDRs) are abundant in eukaryotic
proteomes and play a wide variety of essential roles. Instead of folding into a stable …
proteomes and play a wide variety of essential roles. Instead of folding into a stable …
Phase separation in fungi
Phase separation, in which macromolecules partition into a concentrated phase that is
immiscible with a dilute phase, is involved with fundamental cellular processes across the …
immiscible with a dilute phase, is involved with fundamental cellular processes across the …
Biomolecular condensates regulate cellular electrochemical equilibria
Control of the electrochemical environment in living cells is typically attributed to ion
channels. Here, we show that the formation of biomolecular condensates can modulate the …
channels. Here, we show that the formation of biomolecular condensates can modulate the …
Carbonic anhydrase versatility: from pH regulation to CO2 sensing and metabolism
CT Supuran - Frontiers in Molecular Biosciences, 2023 - frontiersin.org
While the carbonic anhydrase (CA, EC 4.2. 1.1) superfamily of enzymes has been described
primarily as involved only in pH regulation for decades, it also has many other important …
primarily as involved only in pH regulation for decades, it also has many other important …
Recent advances in optical gas sensors for carbon dioxide detection
Carbon dioxide (CO 2) is a colorless and odorless gas. The imbalanced CO 2
concentrations can have detrimental effects, therefore numerous CO 2 gas sensors have …
concentrations can have detrimental effects, therefore numerous CO 2 gas sensors have …
[HTML][HTML] The adenomatous polyposis coli protein 30 years on
Mutations in the gene encoding the Adenomatous polyposis coli protein (APC) were
discovered as driver mutations in colorectal cancers almost 30 years ago. Since then, the …
discovered as driver mutations in colorectal cancers almost 30 years ago. Since then, the …
Integrative regulatory mechanisms of stomatal movements under changing climate
J Zhang, X Chen, Y Song… - Journal of Integrative Plant …, 2024 - Wiley Online Library
Global climate change‐caused drought stress, high temperatures and other extreme
weather profoundly impact plant growth and development, restricting sustainable crop …
weather profoundly impact plant growth and development, restricting sustainable crop …
White-opaque switching in Candida albicans: cell biology, regulation, and function
DR Soll - Microbiology and Molecular Biology Reviews, 2024 - Am Soc Microbiol
Candida albicans remains a major fungal pathogen colonizing humans and
opportunistically invading tissue when conditions are predisposing. Part of the success of C …
opportunistically invading tissue when conditions are predisposing. Part of the success of C …
[HTML][HTML] Study liquid–liquid phase separation with optical microscopy: A methodology review
Intracellular liquid–liquid phase separation (LLPS) is a critical process involving the dynamic
association of biomolecules and the formation of non-membrane compartments, playing a …
association of biomolecules and the formation of non-membrane compartments, playing a …
Liquid-liquid phase separation: a new perspective on respiratory diseases
L Wang, Y Wang, Z Ke, Z Wang, Y Guo… - Frontiers in …, 2024 - frontiersin.org
Liquid-liquid phase separation (LLPS) is integral to various biological processes, facilitating
signal transduction by creating a condensed, membrane-less environment that plays crucial …
signal transduction by creating a condensed, membrane-less environment that plays crucial …