The pathophysiology and treatment of glaucoma: a review
Importance Glaucoma is a worldwide leading cause of irreversible vision loss. Because it
may be asymptomatic until a relatively late stage, diagnosis is frequently delayed. A general …
may be asymptomatic until a relatively late stage, diagnosis is frequently delayed. A general …
Primary open-angle glaucoma
RN Weinreb, CKS Leung, JG Crowston… - Nature reviews Disease …, 2016 - nature.com
Glaucoma is an optic neuropathy that is characterized by the progressive degeneration of
the optic nerve, leading to visual impairment. Glaucoma is the main cause of irreversible …
the optic nerve, leading to visual impairment. Glaucoma is the main cause of irreversible …
Primary open-angle glaucoma preferred practice pattern®
SJ Gedde, K Vinod, MM Wright, KW Muir, JT Lind… - Ophthalmology, 2021 - Elsevier
Background Primary open angle glaucoma (POAG) is a chronic, progressive ocular disease
causing loss of the optic nerve rim and retinal nerve fiber layer (RNFL) with associated …
causing loss of the optic nerve rim and retinal nerve fiber layer (RNFL) with associated …
[PDF][PDF] Primary open-angle glaucoma preferred practice pattern® guidelines
Primary open-angle glaucoma (POAG) is a chronic, progressive optic neuropathy in adults
in which there is a characteristic acquired atrophy of the optic nerve and loss of retinal …
in which there is a characteristic acquired atrophy of the optic nerve and loss of retinal …
Genome-wide analyses identify 68 new loci associated with intraocular pressure and improve risk prediction for primary open-angle glaucoma
Glaucoma is the leading cause of irreversible blindness globally. Despite its gravity, the
disease is frequently undiagnosed in the community. Raised intraocular pressure (IOP) is …
disease is frequently undiagnosed in the community. Raised intraocular pressure (IOP) is …
Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma
Primary open-angle glaucoma (POAG) is a leading cause of blindness worldwide. To
identify new susceptibility loci, we performed meta-analysis on genome-wide association …
identify new susceptibility loci, we performed meta-analysis on genome-wide association …
Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus
Central corneal thickness (CCT) is associated with eye conditions including keratoconus
and glaucoma. We performed a meta-analysis on> 20,000 individuals in European and …
and glaucoma. We performed a meta-analysis on> 20,000 individuals in European and …
Genetic variants underlying risk of endometriosis: insights from meta-analysis of eight genome-wide association and replication datasets
BACKGROUND Endometriosis is a heritable common gynaecological condition influenced
by multiple genetic and environmental factors. Genome-wide association studies (GWASs) …
by multiple genetic and environmental factors. Genome-wide association studies (GWASs) …
Genetics of glaucoma
Genetic and genomic studies, including genome-wide association studies (GWAS) have
accelerated the discovery of genes contributing to glaucoma, the leading cause of …
accelerated the discovery of genes contributing to glaucoma, the leading cause of …
A multiethnic genome-wide association study of primary open-angle glaucoma identifies novel risk loci
H Choquet, S Paylakhi, SC Kneeland, KK Thai… - Nature …, 2018 - nature.com
Primary open-angle glaucoma (POAG) is a leading cause of irreversible vision loss, yet
much of the genetic risk remains unaccounted for, especially in African-Americans who have …
much of the genetic risk remains unaccounted for, especially in African-Americans who have …