The microspheres/hydrogels scaffolds based on the proteins, nucleic acids, or polysaccharides composite as carriers for tissue repair: A review

X Li, X Wu - International Journal of Biological Macromolecules, 2023 - Elsevier
There are many studies on specific macromolecules and their contributions to tissue repair.
Macromolecules have supporting and protective effects in organisms and can help regrow …

Carrier-free nanodrug based on Co-assembly of methylprednisolone dimer and rutin for combined treatment of spinal cord injury

H Wang, F Lin, Y Wu, W Guo, X Chen, C **ao… - ACS nano, 2023 - ACS Publications
Spinal cord injury (SCI), which is characterized by excessive inflammatory cell infiltration
and accumulation of oxidative substance, would severely impede neurological functional …

[HTML][HTML] Breaking barriers in cancer management: The promising role of microsphere conjugates in cancer diagnosis and therapy

A Gupta, S Kulkarni, S Soman, M Saha… - International Journal of …, 2024 - Elsevier
Cancer is a significant worldwide health concern, and there is a demand for ongoing
breakthroughs in treatment techniques. Microspheres are among the most studied drug …

Biodegradable and injectable poly (vinyl alcohol) microspheres in silk sericin-based hydrogel for the controlled release of antimicrobials: application to deep full …

BM Bakadia, A Zhong, X Li, BOO Boni… - … Composites and Hybrid …, 2022 - Springer
Deep full-thickness burn wounds are prone to multi-drug resistant (MDR) infections following
injury, which extends the healing time. Thus, providing a bioactive hydrogel dressing with …

Polyurethane-based nanofibrous mat containing porphyrin with photosensitivity and bactericidal properties can promote cutaneous tissue healing in rats

S Saghebasl, H Amini, A Nobakht, S Haiaty… - Journal of …, 2023 - Springer
The regeneration of cutaneous tissue is one of the most challenging issues in human
regenerative medicine. To date, several studies have been done to promote cutaneous …

A selective, hydrogel‐based prodrug delivery system efficiently activates a suicide gene to remove undifferentiated human stem cells within neural grafts

KCL Law, N Mahmoudi, ZE Zadeh… - Advanced Functional …, 2023 - Wiley Online Library
The directed differentiation of human pluripotent stem cells (hPSCs) into defined populations
has advanced regenerative medicine, especially for Parkinson's disease where clinical trials …

Microneedle/CD-MOF-mediated transdural controlled release of methylprednisolone sodium succinate after spinal cord injury

X Zhai, K Chen, X Wei, H Zhang, H Yang, K Jiao… - Journal of Controlled …, 2023 - Elsevier
A new method of transdural delivering drugs to the spinal cord has been developed,
involving the use of microneedles (MNs) and a β-cyclodextrin metal-organic framework (CD …

Controlled Interfacial Polymer Self‐Assembly Coordinates Ultrahigh Drug Loading and Zero‐Order Release in Particles Prepared under Continuous Flow

P Zhang, Y Liu, G Feng, C Li, J Zhou, C Du… - Advanced …, 2023 - Wiley Online Library
Microparticles are successfully engineered through controlled interfacial self‐assembly of
polymers to harmonize ultrahigh drug loading with zero‐order release of protein payloads …

Preparation and application of hemostatic microspheres containing biological macromolecules and others

Z Ren, Y Wang, H Wu, H Cong, B Yu, Y Shen - International Journal of …, 2024 - Elsevier
Bleeding from uncontrollable wounds can be fatal, and the body's clotting mechanisms are
unable to control bleeding in a timely and effective manner in emergencies such as …

Specific interaction based drug loading strategies

H Yu, S Zhang, H Yang, J Miao, X Ma, W **ong… - Nanoscale …, 2023 - pubs.rsc.org
Drug carriers have been commonly used for drug control release, enhancing drug efficacy
and/or minimizing side-effects. However, it is still difficult to get a high loading efficiency …