The importance of antimicrobial resistance in medical mycology

NAR Gow, C Johnson, J Berman, AT Coste… - Nature …, 2022 - nature.com
Prior to the SARS-CoV-2 pandemic, antibiotic resistance was listed as the major global
health care priority. Some analyses, including the O'Neill report, have predicted that deaths …

[HTML][HTML] Antifungal drug-resistance mechanisms in Candida biofilms

J Kaur, CJ Nobile - Current opinion in microbiology, 2023 - Elsevier
Highlights•Few classes of antifungal drugs currently exist to treat fungal infections.•Infections
caused by Candida biofilms can be resistant to known antifungal drugs.•Growth in the …

Treatment strategies for cryptococcal infection: challenges, advances and future outlook

KR Iyer, NM Revie, C Fu, N Robbins… - Nature Reviews …, 2021 - nature.com
Cryptococcus spp., in particular Cryptococcus neoformans and Cryptococcus gattii, have an
enormous impact on human health worldwide. The global burden of cryptococcal meningitis …

Cryptococcus neoformans, a global threat to human health

Y Zhao, L Ye, F Zhao, L Zhang, Z Lu, T Chu… - Infectious Diseases of …, 2023 - mednexus.org
Background Emerging fungal pathogens pose important threats to global public health. The
World Health Organization has responded to the rising threat of traditionally neglected …

Porous organic polymers for drug delivery: Hierarchical pore structures, variable morphologies, and biological properties

Y Tang, A Varyambath, Y Ding, B Chen, X Huang… - Biomaterials …, 2022 - pubs.rsc.org
Porous organic polymers have received considerable attention in recent years because of
their applicability as biomaterials. In particular, their hierarchical pore structures, variable …

A probiotic nanozyme hydrogel regulates vaginal microenvironment for Candida vaginitis therapy

G Wei, Q Liu, X Wang, Z Zhou, X Zhao, W Zhou… - Science …, 2023 - science.org
Molecular therapeutics are limited for Candida vaginitis because they damage normal cells
and tissues of vagina, aggravating the imbalance of vaginal microbiota and increasing the …

Current progress on epidemiology, diagnosis, and treatment of sporotrichosis and their future trends

AM Rodrigues, SS Gonçalves, JA de Carvalho… - Journal of Fungi, 2022 - mdpi.com
Sporotrichosis, a human and animal disease caused by Sporothrix species, is the most
important implantation mycosis worldwide. Sporothrix taxonomy has improved in recent …

Mechanisms of antifungal properties of metal nanoparticles

YN Slavin, H Bach - Nanomaterials, 2022 - mdpi.com
Highlights What are the main findings? Mechanisms by which nanoparticles exert their
damage on fungi were described. Transcriptomic studies regarding exposure to …

A small molecule produced by Lactobacillus species blocks Candida albicans filamentation by inhibiting a DYRK1-family kinase

J MacAlpine, M Daniel-Ivad, Z Liu, J Yano… - Nature …, 2021 - nature.com
The fungus Candida albicans is an opportunistic pathogen that can exploit imbalances in
microbiome composition to invade its human host, causing pathologies ranging from vaginal …

Flexible modulation of cellular activities with cationic photosensitizers: insights of alkyl chain length on reactive oxygen species antimicrobial mechanisms

L Zheng, Y Zhu, Y Sun, S **a, S Duan, B Yu… - Advanced …, 2023 - Wiley Online Library
Cationic photosensitizers have good binding ability with negatively charged bacteria and
fungi, exhibiting broad applications potential in antimicrobial photodynamic therapy (aPDT) …