Mathematical models of developmental vascular remodelling: A review
Over the past 40 years, there has been a strong focus on the development of mathematical
models of angiogenesis, while developmental remodelling has received little such attention …
models of angiogenesis, while developmental remodelling has received little such attention …
Remodeling of the microvasculature: may the blood flow be with you
R Santamaría, M González-Álvarez, R Delgado… - Frontiers in …, 2020 - frontiersin.org
The vasculature ensures optimal delivery of nutrients and oxygen throughout the body, and
to achieve this function it must continually adapt to varying tissue demands. Newly formed …
to achieve this function it must continually adapt to varying tissue demands. Newly formed …
Loading-driven PI3K/Akt signaling and erythropoiesis enhanced angiogenesis and osteogenesis in a postmenopausal osteoporosis mouse model
A Abdurahman, X Li, J Li, D Liu, L Zhai, X Wang… - Bone, 2022 - Elsevier
Bone vasculature influences osteogenesis and haematopoiesis in the bone
microenviroment. Mechanical loading has been shown to stimulate the formation of …
microenviroment. Mechanical loading has been shown to stimulate the formation of …
Red blood cell dynamics in extravascular biological tissues modelled as canonical disordered porous media
The dynamics of blood flow in the smallest vessels and passages of the human body, where
the cellular character of blood becomes prominent, plays a dominant role in the transport …
the cellular character of blood becomes prominent, plays a dominant role in the transport …
Red blood cell lingering modulates hematocrit distribution in the microcirculation
The distribution of red blood cells (RBCs) in the microcirculation determines the oxygen
delivery and solute transport to tissues. This process relies on the partitioning of RBCs at …
delivery and solute transport to tissues. This process relies on the partitioning of RBCs at …
Angiogenesis is uncoupled from osteogenesis during calvarial bone regeneration
MG Bixel, KK Sivaraj, M Timmen… - Nature …, 2024 - nature.com
Bone regeneration requires a well-orchestrated cellular and molecular response including
robust vascularization and recruitment of mesenchymal and osteogenic cells. In femoral …
robust vascularization and recruitment of mesenchymal and osteogenic cells. In femoral …
Angiogenic microvascular wall shear stress patterns revealed through three-dimensional Red blood cell resolved modeling
The wall shear stress (WSS) exerted by blood flowing through microvascular capillaries is
an established driver of new blood vessel growth, or angiogenesis. Such adaptations are …
an established driver of new blood vessel growth, or angiogenesis. Such adaptations are …
A critical review of multiphase modelling of blood flow in human cardiovascular system
In the human body, blood acts as a transporter of oxygen and other nutrients as well as
carbon dioxide and other waste materials to and from all the organs. Therefore, continuous …
carbon dioxide and other waste materials to and from all the organs. Therefore, continuous …
Capillary pruning couples tissue perfusion and oxygenation with cardiomyocyte maturation in the postnatal mouse heart
R Santamaría, J Cruz-Caballero, P Gkontra… - Frontiers in Cell and …, 2023 - frontiersin.org
Introduction: Removal of poorly perfused capillaries by pruning contributes to remodeling
the microvasculature to optimize oxygen and nutrient delivery. Blood flow drives this process …
the microvasculature to optimize oxygen and nutrient delivery. Blood flow drives this process …
Compressed vessels bias red blood cell partitioning at bifurcations in a hematocrit-dependent manner: Implications in tumor blood flow
The tumor microenvironment is abnormal and associated with tumor tissue hypoxia,
immunosuppression, and poor response to treatment. One important abnormality present in …
immunosuppression, and poor response to treatment. One important abnormality present in …