Ribonucleases (RNases) are mediators in most reactions of RNA metabolism. In recent
years, there has been a surge of new information about RNases and the roles they play in …

RNase E is an essential endonuclease that is abundant in many bacteria and plays an
important part in all aspects of RNA metabolism. It functions as part of a large …

Coexpression of proteins in response to pathway-inducing signals is the founding paradigm
of gene regulation. However, it remains unexplored whether the relative abundance of co …

Men may not be able to multitask, but it is emerging that proteins can. This capacity of
proteins to exhibit more than one function is termed protein moonlighting, and, surprisingly …

It is not often realized that the absolute protein specificity is an exception rather than a rule.
Two major kinds of protein multi-specificities are promiscuity and moonlighting. This review …

mRNA degradation is an important mechanism for controlling gene expression in bacterial
cells. This process involves the orderly action of a battery of cellular endonucleases and …

The continuous degradation and synthesis of prokaryotic mRNAs not only give rise to the
metabolic changes that are required as cells grow and divide but also rapid adaptation to …

The genome of the Gram-positive soil bacterium Bacillus subtilis encodes three potential
diadenylate cyclases that may synthesize the signaling nucleotide cyclic di-AMP (c-di-AMP) …

In contrast to Escherichia coli, initiation of mRNA decay in Gram‐positive organisms is
poorly understood. We studied the fate of the highly structured RNAs generated by …

Moonlighting proteins are defined as proteins with two or more functions that are unrelated
and independent to each other, so that inactivation of one of them should not affect the …