New-generation advanced PROTACs as potential therapeutic agents in cancer therapy

C Wang, Y Zhang, W Chen, Y Wu, D **ng - Molecular Cancer, 2024 - Springer
Proteolysis-targeting chimeras (PROTACs) technology has garnered significant attention
over the last 10 years, representing a burgeoning therapeutic approach with the potential to …

Cancer nanotechnology: current status and perspectives

JA Kemp, YJ Kwon - Nano convergence, 2021 - Springer
Modern medicine has been waging a war on cancer for nearly a century with no tangible
end in sight. Cancer treatments have significantly progressed, but the need to increase …

A MOF-based potent ferroptosis inducer for enhanced radiotherapy of triple negative breast cancer

L Zeng, S Ding, Y Cao, C Li, B Zhao, Z Ma, J Zhou… - ACS …, 2023 - ACS Publications
Radiotherapy (RT) is one of the important clinical treatments for local control of triple-
negative breast cancer (TNBC), but radioresistance still exists. Ferroptosis has been …

[HTML][HTML] Crosstalk between ferroptosis and cuproptosis: From mechanism to potential clinical application

N Liu, M Chen - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Ferroptosis and cuproptosis, regulated forms of cell death resulting from metal ion
accumulation, are closely related in terms of occurrence, cell metabolism, signaling …

Advancing nanotechnology for neoantigen-based cancer theranostics

J Zou, Y Zhang, Y Pan, Z Mao, X Chen - Chemical Society Reviews, 2024 - pubs.rsc.org
Neoantigens play a pivotal role in the field of tumour therapy, encompassing the stimulation
of anti-tumour immune response and the enhancement of tumour targeting capability …

The applications of nanozymes in cancer therapy: based on regulating pyroptosis, ferroptosis and autophagy of tumor cells

Y Zhang, W Yu, M Chen, B Zhang, L Zhang, P Li - Nanoscale, 2023 - pubs.rsc.org
Nanozymes are nanomaterials with catalytic properties similar to those of natural enzymes,
and they have recently been collectively identified as a class of innovative artificial enzymes …

Advances in radiotherapy and immunity in hepatocellular carcinoma

Y Yang, L **ong, M Li, P Jiang, J Wang, C Li - Journal of Translational …, 2023 - Springer
Primary liver cancer is one of the most common malignant tumours worldwide; it caused
approximately 830,000 deaths in 2020. Hepatocellular carcinoma (HCC) is the most …

Self‐Cascade Nanozyme Reactor as a Cuproptosis Inducer Synergistic Inhibition of Cellular Respiration Boosting Radioimmunotherapy

R Li, W Zhao, Z Han, N Feng, T Wu, H **ong, W Jiang - Small, 2024 - Wiley Online Library
Intrinsic or acquired radioresistance remained an important challenge in the successful
management of cancer. Herein, a novel “smart” multifunctional copper‐based …

All‐in‐one biomimetic nanoplatform based on hollow polydopamine nanoparticles for synergistically enhanced radiotherapy of colon cancer

L Gong, Y Zhang, J Zhao, Y Zhang, K Tu, L Jiao, Q Xu… - Small, 2022 - Wiley Online Library
Even though radiotherapy is the most important therapeutic strategy for colon cancer
treatment, there is an enormous demand to improve radiosensitivity in solid tumor …

Synthesis and bioapplication of emerging nanomaterials of Hafnium

D Skrodzki, M Molinaro, R Brown, P Moitra, D Pan - ACS nano, 2024 - ACS Publications
A significant amount of progress in nanotechnology has been made due to the development
of engineered nanoparticles. The use of metallic nanoparticles for various biomedical …