Infection-induced inflammation and cerebral injury in preterm infants
Preterm birth and infectious diseases are the most common causes of neonatal and early
childhood deaths worldwide. The rates of preterm birth have increased over recent decades …
childhood deaths worldwide. The rates of preterm birth have increased over recent decades …
Chorioamnionitis as a risk factor for bronchopulmonary dysplasia: a systematic review and meta-analysis
L Hartling, Y Liang, T Lacaze-Masmonteil - Archives of Disease in …, 2012 - fn.bmj.com
Objective To conduct a systematic review of the association between chorioamnionitis (CA)
and bronchopulmonary dysplasia (BPD) in preterm infants. Methods The authors searched …
and bronchopulmonary dysplasia (BPD) in preterm infants. Methods The authors searched …
Intrauterine inflammation, insufficient to induce parturition, still evokes fetal and neonatal brain injury
MA Elovitz, AG Brown, K Breen, L Anton… - International Journal of …, 2011 - Elsevier
Exposure to prenatal inflammation is a known risk factor for long term neurobehavioral
disorders including cerebral palsy, schizophrenia, and autism. Models of systemic …
disorders including cerebral palsy, schizophrenia, and autism. Models of systemic …
Selective impairment of TLR-mediated innate immunity in human newborns: neonatal blood plasma reduces monocyte TNF-α induction by bacterial lipopeptides …
O Levy, KA Zarember, RM Roy, C Cywes… - The Journal of …, 2004 - journals.aai.org
Newborns are at increased risk of overwhelming infection, yet the mechanisms underlying
this susceptibility are incompletely defined. In this study we report a striking 1-to 3-log …
this susceptibility are incompletely defined. In this study we report a striking 1-to 3-log …
[HTML][HTML] The elusive role of placental macrophages: the Hofbauer cell
In this review, we discuss the often overlooked tissue-resident fetal macrophages, Hofbauer
cells, which are found within the chorionic villi of the human placenta. Hofbauer cells have …
cells, which are found within the chorionic villi of the human placenta. Hofbauer cells have …
Oxidative stress and bronchopulmonary dysplasia
S Perrone, ML Tataranno… - Journal of clinical …, 2012 - journals.lww.com
Bronchopulmonary dysplasia (BPD) is the major cause of pulmonary disease in infants. The
pathophysiology and management of BPD changed with the improvement of neonatal …
pathophysiology and management of BPD changed with the improvement of neonatal …
Placenta and fetal growth restriction
CM Salafia, AK Charles, EM Maas - Clinical obstetrics and …, 2006 - journals.lww.com
The placenta, as the vector for all maternal-fetal oxygen and nutrient exchange, is a principal
influence on birthweight. Placental weight summarizes laterally expanding growth of the …
influence on birthweight. Placental weight summarizes laterally expanding growth of the …
Chorioamnionitis: important risk factor or innocent bystander for neonatal outcome?
W Thomas, CP Speer - Neonatology, 2011 - karger.com
Chorioamnionitis as a major risk factor for spontaneous preterm birth, especially at earlier
gestational ages, contributes to prematurity-associated mortality and morbidity. A gestation …
gestational ages, contributes to prematurity-associated mortality and morbidity. A gestation …
Antenatal suppression of IL-1 protects against inflammation-induced fetal injury and improves neonatal and developmental outcomes in mice
M Nadeau-Vallée, PY Chin, L Belarbi… - The Journal of …, 2017 - journals.aai.org
MN-V, SP, SAR, SG, and SC designed the research studies; MN-V., P.-YC, LB, M.-ÈB, SP,
MHB, AM, AB-R., DJS, AL-M., XH, A. Boudreault, AC, IB, and SG conducted experiments; …
MHB, AM, AB-R., DJS, AL-M., XH, A. Boudreault, AC, IB, and SG conducted experiments; …
[HTML][HTML] Mild/asymptomatic COVID-19 in unvaccinated pregnant mothers impairs neonatal immune responses
Maternal SARS-CoV-2 infection triggers placental inflammation and alters cord blood
immune cell composition. However, most studies focus on outcomes of severe maternal …
immune cell composition. However, most studies focus on outcomes of severe maternal …