Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by
motor and non-motor symptoms. More than 200 years after its first clinical description, PD …

A full understanding of Parkinson's Disease etiopathogenesis and of the causes of the
preferential vulnerability of nigrostriatal dopaminergic neurons is still an unsolved puzzle. A …

The novel object recognition test (NOR) test is a two trial cognitive paradigm that assesses
recognition memory. Recognition memory is disturbed in a range of human disorders and …

Parkinson's disease (PD) is a complex, multisystem disorder characterised by α-synuclein
(SNCA) pathology, degeneration of nigrostriatal dopaminergic neurons, multifactorial …

The administration of reserpine to rodents was one of the first models used to investigate the
pathophysiology and screening for potential treatments of P arkinson's disease (PD). The …

Parkinson's disease (PD) is a widespread neurodegenerative disorder occurs due to the
degradation of dopaminergic neurons present in the substantia nigra pars compacta (SNpc) …

Reserpine is an effective drug for the clinical treatment of hypertension. It also induces
Parkinson's disease (PD)-like symptoms in humans and animals possible through the …

Cannabidiol (CBD) is a non-psychotomimetic compound from Cannabis sativa that presents
antipsychotic, anxiolytic, anti-inflammatory, and neuroprotective effects. In Parkinson's …

Parkinson's disease (PD) is the second most common neurodegenerative disease. The
main symptoms are motor signs such as resting tremor and difficulty in initializing …

Parkinson's disease (PD) is a significant health issue because it gradually damages the
nervous system. α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors …