Therapeutic potential of phenolic compounds in medicinal plants—Natural health products for human health

W Sun, MH Shahrajabian - Molecules, 2023 - mdpi.com
Phenolic compounds and flavonoids are potential substitutes for bioactive agents in
pharmaceutical and medicinal sections to promote human health and prevent and cure …

Recent advance on carbamate-based cholinesterase inhibitors as potential multifunctional agents against Alzheimer's disease

H Zhang, Y Wang, Y Wang, X Li, S Wang… - European Journal of …, 2022 - Elsevier
Abstract Alzheimer's disease (AD), as the fourth leading cause of death among the elderly
worldwide, has brought enormous challenge to the society. Due to its extremely complex …

New insights into dietary pterostilbene: sources, metabolism, and health promotion effects

S Nagarajan, S Mohandas, K Ganesan, B Xu… - Molecules, 2022 - mdpi.com
Pterostilbene (PTS), a compound most abundantly found in blueberries, is a natural analog
of resveratrol. Several plant species, such as peanuts and grapes, produce PTS. While …

Overcoming the intestinal barrier: a look into targeting approaches for improved oral drug delivery systems

Y Xu, N Shrestha, V Préat, A Beloqui - Journal of controlled release, 2020 - Elsevier
Oral drug administration is one of the most preferred and simplest routes among both
patients and formulation scientists. Nevertheless, orally delivery of some of the most widely …

A review of dietary stilbenes: Sources and bioavailability

T El Khawand, A Courtois, J Valls, T Richard… - Phytochemistry …, 2018 - Springer
Stilbenes are a class of phenolic metabolites found in various edible plants, such as
grapevine, berries and peanuts. Their bioactivitiy and their potential benefits for human …

Pterostilbene in cancer therapy

E Obrador, R Salvador-Palmer, A Jihad-Jebbar… - Antioxidants, 2021 - mdpi.com
Natural polyphenols are organic chemicals which contain phenol units in their structures
and possess antitumor properties. However, a key problem is their short half-life and low …

Strategies to improve resveratrol systemic and topical bioavailability: An update

S Intagliata, MN Modica, LM Santagati, L Montenegro - Antioxidants, 2019 - mdpi.com
In recent years, a great deal of attention has been paid to natural compounds due to their
many biological effects. Polyphenols are a class of plant derivatives that have been widely …

Recent advances in synthesis, bioactivity, and pharmacokinetics of pterostilbene, an important analog of resveratrol

Y Liu, Y You, J Lu, X Chen, Z Yang - Molecules, 2020 - mdpi.com
Pterostilbene is a natural 3, 5-dimethoxy analog of resveratrol. This stilbene compound has
a strong bioactivity and exists widely in Dalbergia and Vaccinium spp. Besides natural …

Recent advances in health benefits of stilbenoids

YC Koh, CT Ho, MH Pan - Journal of agricultural and food …, 2021 - ACS Publications
Biological targeting or molecular targeting is the main strategy in drug development and
disease prevention. However, the problem of “off-targets” cannot be neglected. Naturally …

Transporter-mediated drug delivery

G Gyimesi, MA Hediger - Molecules, 2023 - mdpi.com
Transmembrane transport of small organic and inorganic molecules is one of the
cornerstones of cellular metabolism. Among transmembrane transporters, solute carrier …