Over the past 15 years there has been an explosion of research on the dynamical properties
of proteins, largely driven by the emergence of a handful of techniques that are sensitive to …

Under stress, certain eukaryotic proteins and RNA assemble to form membraneless
organelles known as stress granules. The most well-studied stress granule components are …

While extracting dynamics parameters from backbone 15 N relaxation measurements in
proteins has become routine over the past two decades, it is increasingly recognized that …

Ubiquilin/PLIC proteins belong to the family of UBL–UBA proteins implicated in the
regulation of the ubiquitin-dependent proteasomal degradation of cellular proteins. A human …

During tumor progression, EphA2 receptor can gain ligand-independent pro-oncogenic
functions due to Akt activation and reduced ephrin-A ligand engagement. The effects can be …

The low-affinity immunoglobulin E (IgE) receptor, CD23 (Fc ε RII), binds both IgE and CD21
and, through these interactions, regulates the synthesis of IgE, the antibody isotype that …

Intrinsically disordered proteins and intrinsically disordered regions (IDRs) are ubiquitous in
the eukaryotic proteome. The description and understanding of their conformational …

Understanding the molecular determinants underlying protein function requires the
characterization of both structure and dynamics at atomic resolution. Nuclear relaxation …

Conformational heterogeneity is key to the function of many biomacromolecules, but only a
few groups have tried to characterize it until recently. Now, thanks to the increased …

Polyubiquitination, a critical protein post-translational modification, signals for a diverse set
of cellular events via the different isopeptide linkages formed between the C terminus of one …