Age-related macular degeneration: a review
Importance Age-related macular degeneration (AMD) affects approximately 20 million
people in the US and 196 million people worldwide. AMD is a leading cause of severe …
people in the US and 196 million people worldwide. AMD is a leading cause of severe …
AI in the clinical management of GA: a novel therapeutic universe requires novel tools
GS Reiter, J Mai, S Riedl, K Birner, S Frank… - Progress in Retinal and …, 2024 - Elsevier
Regulatory approval of the first two therapeutic substances for the management of
geographic atrophy (GA) secondary to age-related macular degeneration (AMD) is a major …
geographic atrophy (GA) secondary to age-related macular degeneration (AMD) is a major …
Oral antioxidant and lutein/zeaxanthin supplements slow geographic atrophy progression to the fovea in age-related macular degeneration
Purpose To determine whether oral micronutrient supplementation slows geographic
atrophy (GA) progression in age-related macular degeneration (AMD). Design Post hoc …
atrophy (GA) progression in age-related macular degeneration (AMD). Design Post hoc …
[HTML][HTML] Disease activity and therapeutic response to pegcetacoplan for geographic atrophy identified by deep learning-based analysis of OCT
Purpose To quantify morphological changes of the photoreceptors (PRs) and retinal pigment
epithelium (RPE) layers under pegcetacoplan therapy in geographic atrophy (GA) using …
epithelium (RPE) layers under pegcetacoplan therapy in geographic atrophy (GA) using …
Retinal vasculitis after intravitreal pegcetacoplan: report from the ASRS Research and Safety in Therapeutics (ReST) Committee
AJ Witkin, GJ Jaffe, SK Srivastava… - Journal of …, 2024 - journals.sagepub.com
Purpose: To analyze post-marketing cases of retinal vasculitis after intravitreal
pegcetacoplan. Methods: The American Society of Retina Specialists (ASRS) Research and …
pegcetacoplan. Methods: The American Society of Retina Specialists (ASRS) Research and …
[HTML][HTML] A review of ophthalmology education in the era of generative artificial intelligence
Purpose To explore the integration of generative AI, specifically large language models
(LLMs), in ophthalmology education and practice, addressing their applications, benefits …
(LLMs), in ophthalmology education and practice, addressing their applications, benefits …
[PDF][PDF] Complement regulation in the eye: implications for age-related macular degeneration
GA Wilke, RS Apte - Journal of Clinical Investigation, 2024 - Am Soc Clin Investig
Careful regulation of the complement system is critical for enabling complement proteins to
titrate immune defense while also preventing collateral tissue damage from poorly controlled …
titrate immune defense while also preventing collateral tissue damage from poorly controlled …
Deep-learning-based automated measurement of outer retinal layer thickness for use in the assessment of age-related macular degeneration, applicable to both …
Effective biomarkers are required for assessing the progression of age-related macular
degeneration (AMD), a prevalent and progressive eye disease. This paper presents a deep …
degeneration (AMD), a prevalent and progressive eye disease. This paper presents a deep …
[HTML][HTML] Different Therapeutic Approaches for Dry and Wet AMD
Age-related macular degeneration (AMD) is the most common cause of irreversible loss of
central vision in elderly subjects, affecting men and women equally. It is a degenerative …
central vision in elderly subjects, affecting men and women equally. It is a degenerative …
Complement inhibitors for the treatment of geographic atrophy
EY Chew - The Lancet, 2023 - thelancet.com
Comment www. thelancet. com Vol 402 October 21, 2023 1397 events, including four cases
of infectious endophthalmitis and three cases of optic ischaemic neuropathy. 2 These are …
of infectious endophthalmitis and three cases of optic ischaemic neuropathy. 2 These are …