Legionella species are environmental gram-negative bacteria able to cause a severe form of
pneumonia in humans known as Legionnaires' disease. Since the identification of …

Type IV secretion systems (T4SSs) are versatile multiprotein nanomachines spanning the
entire cell envelope in Gram‐negative and Gram‐positive bacteria. They play important …

Small GTPases use GDP/GTP alternation to actuate a variety of functional switches that are
pivotal for cell dynamics. The GTPase switch is turned on by GEFs, which stimulate …

Abbreviations used in this paper: ANOVA, analysis of variance; FKBP, FK506 binding
protein; FRB, FKBP12-rapamycin binding; iRFP, infra-RFP; nMDP, normalized mean …

Polyphosphoinositides (PPIn) are an important family of phospholipids located on the
cytoplasmic leaflet of eukaryotic cell membranes. Collectively, they are critical for the …

Vesicular trafficking in eukaryotes is an important process for the intracellular transport of
molecules such as soluble proteins, membrane receptors, or neurotransmitters. The spatial …

L egionella species are ubiquitous, waterborne bacteria that thrive in numerous ecological
niches. Yet, in contrast to many other environmental bacteria, L egionella spp. are also able …

Specific lipid species play central roles in cell biology. Their presence or enrichment in
individual membranes can control properties or direct protein localization and/or activity …

β-propellers that bind polyphosphoinositides (PROPPINs), a eukaryotic WD-40 motif-
containing protein family, bind via their predicted β-propeller fold the polyphosphoinositides …

Many bacterial pathogens employ multicomponent protein complexes to deliver
macromolecules directly into their eukaryotic host cell to promote infection. Some Gram …