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New insights into the development of the human cerebral cortex
The cerebral cortex constitutes more than half the volume of the human brain and is
presumed to be responsible for the neuronal computations underlying complex phenomena …
presumed to be responsible for the neuronal computations underlying complex phenomena …
[HTML][HTML] Fetal brain MRI atlases and datasets: A review
Fetal brain development is a complex process involving different stages of growth and
organization which are crucial for the development of brain circuits and neural connections …
organization which are crucial for the development of brain circuits and neural connections …
Neural substrate and clinical significance of general movements: an update
M Hadders‐Algra - Developmental Medicine & Child Neurology, 2018 - Wiley Online Library
General movements are present from early fetal life to 3 to 5 months corrected age. Atypical
general movements, especially in the last, so‐called fidgety general movement phase, are …
general movements, especially in the last, so‐called fidgety general movement phase, are …
[HTML][HTML] The enigmatic fetal subplate compartment forms an early tangential cortical nexus and provides the framework for construction of cortical connectivity
I Kostović - Progress in neurobiology, 2020 - Elsevier
The most prominent transient compartment of the primate fetal cortex is the deep, cell-
sparse, synapse-containing subplate compartment (SPC). The developmental role of the …
sparse, synapse-containing subplate compartment (SPC). The developmental role of the …
Neuronal impact of patient-specific aberrant NRXN1α splicing
NRXN1 undergoes extensive alternative splicing, and non-recurrent heterozygous deletions
in NRXN1 are strongly associated with neuropsychiatric disorders. We establish that human …
in NRXN1 are strongly associated with neuropsychiatric disorders. We establish that human …
Genetic insights and neurobiological implications from NRXN1 in neuropsychiatric disorders
Many neuropsychiatric and neurodevelopmental disorders commonly share genetic risk
factors. To date, the mechanisms driving the pathogenesis of these disorders, particularly …
factors. To date, the mechanisms driving the pathogenesis of these disorders, particularly …
New perspective on sustained antidepressant effect: focus on neurexins regulating synaptic plasticity
Y Ruan, R Yuan, J He, Y Jiang, S Chu, N Chen - Cell Death Discovery, 2024 - nature.com
Depression is highly prevalent globally, however, currently available medications face
challenges such as low response rates and short duration of efficacy. Additionally …
challenges such as low response rates and short duration of efficacy. Additionally …
Autism spectrum disorders: multiple routes to, and multiple consequences of, abnormal synaptic function and connectivity
Autism spectrum disorders (ASDs) are a heterogeneous group of neurodevelopmental
disorders of genetic and environmental etiologies. Some ASD cases are syndromic …
disorders of genetic and environmental etiologies. Some ASD cases are syndromic …
Effect of aging on the human myometrium at single-cell resolution
P Punzon-Jimenez, A Machado-Lopez… - Nature …, 2024 - nature.com
Age-associated myometrial dysfunction can prompt complications during pregnancy and
labor, which is one of the factors contributing to the 7.8-fold increase in maternal mortality in …
labor, which is one of the factors contributing to the 7.8-fold increase in maternal mortality in …
Bridging the translational gap: what can synaptopathies tell us about autism?
Multiple molecular pathways and cellular processes have been implicated in the
neurobiology of autism and other neurodevelopmental conditions. There is a current focus …
neurobiology of autism and other neurodevelopmental conditions. There is a current focus …