Pharmacogenomics in practice: A review and implementation guide

D Kabbani, R Akika, A Wahid, AK Daly… - Frontiers in …, 2023 - frontiersin.org
Considerable efforts have been exerted to implement Pharmacogenomics (PGx), the study
of interindividual variations in DNA sequence related to drug response, into routine clinical …

Electronic health information systems to improve disease diagnosis and management at point-of-care in low and middle income countries: a narrative review

T Khubone, B Tlou, TP Mashamba-Thompson - Diagnostics, 2020 - mdpi.com
The purpose of an electronic health information system (EHIS) is to support health care
workers in providing health care services to an individual client and to enable data …

Determining risk of colorectal cancer and starting age of screening based on lifestyle, environmental, and genetic factors

J Jeon, M Du, RE Schoen, M Hoffmeister, PA Newcomb… - Gastroenterology, 2018 - Elsevier
Background & Aims Guidelines for initiating colorectal cancer (CRC) screening are based
on family history but do not consider lifestyle, environmental, or genetic risk factors. We …

Public attitudes toward consent and data sharing in biobank research: a large multi-site experimental survey in the US

SC Sanderson, KB Brothers, ND Mercaldo… - The American Journal of …, 2017 - cell.com
Individuals participating in biobanks and other large research projects are increasingly
asked to provide broad consent for open-ended research use and widespread sharing of …

The clinical sequencing evidence-generating research consortium: integrating genomic sequencing in diverse and medically underserved populations

LM Amendola, JS Berg, CR Horowitz, F Angelo… - The American Journal of …, 2018 - cell.com
The Clinical Sequencing Evidence-Generating Research (CSER) consortium, now in its
second funding cycle, is investigating the effectiveness of integrating genomic (exome or …

Design and anticipated outcomes of the eMERGE‐PGx project: a multicenter pilot for preemptive pharmacogenomics in electronic health record systems

LJ Rasmussen‐Torvik, SC Stallings… - Clinical …, 2014 - Wiley Online Library
We describe here the design and initial implementation of the eMERGE‐PGx project.
eMERGE‐PGx, a partnership of the Electronic Medical Records and Genomics Network and …

Physician-reported benefits and barriers to clinical implementation of genomic medicine: a multi-site IGNITE-network survey

A Owusu Obeng, K Fei, KD Levy, AR Elsey… - Journal of personalized …, 2018 - mdpi.com
Genetic medicine is one of the key components of personalized medicine, but adoption in
clinical practice is still limited. To understand potential barriers and provider attitudes, we …

[HTML][HTML] Engaging patients and consumers in research evidence: applying the conceptual model of patient and family engagement

KL Carman, TA Workman - Patient education and counseling, 2017 - Elsevier
Objective This essay discusses applying the Conceptual Framework for Patient and Family
Engagement to partnerships with patients and consumers to increase their use of research …

Next-generation sequencing informatics: challenges and strategies for implementation in a clinical environment

S Roy, WA LaFramboise… - … of pathology & …, 2016 - meridian.allenpress.com
Context.—Next-generation sequencing (NGS) is revolutionizing the discipline of laboratory
medicine, with a deep and direct impact on patient care. Although it empowers clinical …

Views of primary care providers on testing patients for genetic risks for common chronic diseases

D Hauser, AO Obeng, K Fei, MA Ramos… - Health Affairs, 2018 - healthaffairs.org
We surveyed 488 primary care providers in community and academic practices in New York
City in the period 2014–16 about their views on genetic testing for chronic diseases. The …