Antimicrobial peptides: an update on classifications and databases
Antimicrobial peptides (AMPs) are distributed across all kingdoms of life and are an
indispensable component of host defenses. They consist of predominantly short cationic …
indispensable component of host defenses. They consist of predominantly short cationic …
Membrane targeting cationic antimicrobial peptides
Many short cationic peptides are amphiphilic and are often termed antimicrobial peptides
(AMPs) as they can kill various microorganisms. These AMPs have largely been discovered …
(AMPs) as they can kill various microorganisms. These AMPs have largely been discovered …
[HTML][HTML] The human cathelicidin LL-37—A pore-forming antibacterial peptide and host-cell modulator
The human cathelicidin hCAP18/LL-37 has become a paradigm for the pleiotropic roles of
peptides in host defence. It has a remarkably wide functional repertoire that includes direct …
peptides in host defence. It has a remarkably wide functional repertoire that includes direct …
Effect of divalent cation removal on the structure of gram-negative bacterial outer membrane models
The Gram-negative bacterial outer membrane (GNB-OM) is asymmetric in its lipid
composition with a phospholipid-rich inner leaflet and an outer leaflet predominantly …
composition with a phospholipid-rich inner leaflet and an outer leaflet predominantly …
[HTML][HTML] Lipopolysaccharides at solid and liquid interfaces: models for biophysical studies of the gram-negative bacterial outer membrane
Lipopolysaccharides (LPSs) are a constitutive element of the cell envelope of Gram-
negative bacteria, representing the main lipid in the external leaflet of their outer membrane …
negative bacteria, representing the main lipid in the external leaflet of their outer membrane …
The chemistry and biology of LL-37
MF Burton, PG Steel - Natural product reports, 2009 - pubs.rsc.org
Covering: up to June 2009LL-37 is a human host defence peptide that has a wide range of
biological functions, including antimicrobial and immunomodulatory properties. This review …
biological functions, including antimicrobial and immunomodulatory properties. This review …
Structural Characterization of a Model Gram-Negative Bacterial Surface Using Lipopolysaccharides from Rough Strains of Escherichia coli
Lipopolysaccharides (LPS) make up approximately 75% of the Gram-negative bacterial
outer membrane (OM) surface, but because of the complexity of the molecule, there are very …
outer membrane (OM) surface, but because of the complexity of the molecule, there are very …
Salmonella Membrane Structural Remodeling Increases Resistance to Antimicrobial Peptide LL-37
Gram-negative bacteria are protected from their environment by an outer membrane that is
primarily composed of lipopolysaccharides (LPSs). Under stress, pathogenic serotypes of …
primarily composed of lipopolysaccharides (LPSs). Under stress, pathogenic serotypes of …
Structural plasticity of LL-37 indicates elaborate functional adaptation mechanisms to bacterial target structures
The human cathelicidin LL-37 is a multifunctional peptide of the human innate immune
system. Among the various functions of LL-37, its antimicrobial activity is important in …
system. Among the various functions of LL-37, its antimicrobial activity is important in …
Effects of specific versus nonspecific ionic interactions on the structure and lateral organization of lipopolysaccharides
We report x-ray reflectivity and grazing incidence x-ray diffraction measurements of
lipopolysaccharide (LPS) monolayers at the water-air interface. Our investigations reveal …
lipopolysaccharide (LPS) monolayers at the water-air interface. Our investigations reveal …