The invariant development and transparent body of the nematode Caenorhabditis elegans
enables complete delineation of cell lineages throughout development. Despite extensive …

Understanding how mechanics complement bio-signaling in defining patterns during
morphogenesis is an outstanding challenge. Here, we utilize the multicellular polyp Hydra to …

We present methods that automatically select a linear or nonlinear classifier for red blood
cell (RBC) classification by analyzing the equality of the covariance matrices in Gabor …

Light sheet fluorescence microscopy (LSFM) has emerged as an important imaging modality
to follow biology in live 3D samples over time with reduced phototoxicity and …

Active contours, or snakes, have a wide range of applications in medical image
segmentation. Gradient vector flow (GVF) field, generalized GVF field and other external …

The cytoplasm of a living cell is a dynamic environment through which intracellular
components must move and mix. In motile, rapidly deforming cells such as human …

Animal morphogenesis, the development of an organism's body form, is commonly
perceived as a directed and almost deterministic process. However, noise and stochastic …

Understanding the mechanisms of collective cell migration is crucial for cancer metastasis,
wound healing and many developmental processes. Imaging a migrating cluster in vivo is …

Cell image segmentation plays a central role in numerous biology studies and clinical
applications. As a result, the development of cell image segmentation algorithms with high …

Phase contrast microscopy (PCM) is routinely used for the inspection of adherent cell
cultures in all fields of biology and biomedicine. Key decisions for experimental protocols …