Roles of gut microbial metabolites in diabetic kidney disease

Q Fang, N Liu, B Zheng, F Guo, X Zeng… - Frontiers in …, 2021‏ - frontiersin.org
Diabetes is a highly prevalent metabolic disease that has emerged as a global challenge
due to its increasing prevalence and lack of sustainable treatment. Diabetic kidney disease …

[HTML][HTML] Recent Advances in Molecular Research on Hydrogen Sulfide (H2S) Role in Diabetes Mellitus (DM)—A Systematic Review

C Munteanu, M Rotariu, M Turnea, G Dogaru… - International Journal of …, 2022‏ - mdpi.com
Abundant experimental data suggest that hydrogen sulfide (H2S) is related to the
pathophysiology of Diabetes Mellitus (DM). Multiple molecular mechanisms, including …

Regulation of carbohydrate metabolism by nitric oxide and hydrogen sulfide: Implications in diabetes

S Gheibi, AP Samsonov, S Gheibi, AB Vazquez… - Biochemical …, 2020‏ - Elsevier
Nitric oxide (NO) and hydrogen sulfide (H 2 S) are two gasotransmitters that are produced in
the human body and have a key role in many of the physiological activities of the various …

Hydrogen sulfide in ageing, longevity and disease

SE Wilkie, G Borland, RN Carter, NM Morton… - Biochemical …, 2021‏ - portlandpress.com
Hydrogen sulfide (H2S) modulates many biological processes, including ageing. Initially
considered a hazardous toxic gas, it is now recognised that H2S is produced endogenously …

Hydrogen sulfide attenuates high-fat diet-induced obesity: involvement of mTOR/IKK/NF-κB signaling pathway

M Zhao, Y Cheng, X Wang, X Cui, X Cheng, Q Fu… - Molecular …, 2022‏ - Springer
Obesity has become a public health epidemic worldwide and is associated with many
diseases with high mortality including hypertension, diabetes, and heart disease. High-fat …

Association between serum hydrogen sulfide concentrations and dysglycemia: a population-based study

Z Bahadoran, S Jeddi, P Mirmiran, K Kashfi… - BMC Endocrine …, 2022‏ - Springer
Background and aim Hydrogen sulfide (H2S), a signaling gasotransmitter, is involved in
carbohydrate metabolism. Here, we aimed to assess the potential association between …

Dose-Dependent Effects of Long-Term Administration of Hydrogen Sulfide on Myocardial Ischemia–Reperfusion Injury in Male Wistar Rats: Modulation of RKIP, NF-κB …

S Jeddi, S Gheibi, K Kashfi, M Carlström… - International journal of …, 2020‏ - mdpi.com
Decreased circulating levels of hydrogen sulfide (H2S) are associated with higher mortality
following myocardial ischemia. This study aimed at determining the long-term dose …

Hydrogen sulfide potentiates the favorable metabolic effects of inorganic nitrite in type 2 diabetic rats

S Gheibi, S Jeddi, M Carlström, K Kashfi, A Ghasemi - Nitric Oxide, 2019‏ - Elsevier
Objective Decreased nitric oxide (NO) bioavailability and hydrogen sulfide (H 2 S) deficiency
have been linked with the pathophysiology of type 2 diabetes (T2D). Restoration of NO …

Effects of exogenous hydrogen sulfide on diabetic metabolic disorders in db/db mice are associated with gut bacterial and fungal microbiota

J Liu, W Zhao, ZW Gao, N Liu, WH Zhang… - Frontiers in Cellular and …, 2022‏ - frontiersin.org
The effects of hydrogen sulfide (H2S) on diabetic metabolic disorders are still controversial,
and the mechanisms underlying these effects remain largely unknown. This study was …

Carbon monoxide and β-cell function: Implications for type 2 diabetes mellitus

Z Bahadoran, P Mirmiran, K Kashfi… - Biochemical Pharmacology, 2022‏ - Elsevier
Carbon monoxide (CO), a member of the multifunctional gasotransmitters family produced
by heme oxygenases (ie, HO-1 and HO-2), has received significant attention because of its …