Transforming vaccinology

R Rappuoli, G Alter, B Pulendran - Cell, 2024 - cell.com
The COVID-19 pandemic placed the field of vaccinology squarely at the center of global
consciousness, emphasizing the vital role of vaccines as transformative public health tools …

Immunogenicity, clinical efficacy and safety of additional second COVID‐19 booster vaccines against Omicron and its subvariants: A systematic review

S Chenchula, MB Chandra… - Reviews in Medical …, 2024 - Wiley Online Library
The Omicron variant of severe acute respiratory syndrome coronavirus 2 is a new variant of
concern (VOC) and an emerging subvariant that exhibits heightened infectivity …

Safety and immunogenicity of aerosolised Ad5-nCoV, intramuscular Ad5-nCoV, or inactivated COVID-19 vaccine CoronaVac given as the second booster following …

R Tang, H Zheng, BS Wang, JB Gou… - The Lancet …, 2023 - thelancet.com
Summary Background Aerosolised Ad5-nCoV is the first approved mucosal respiratory
COVID-19 vaccine to be used as a booster after the primary immunisation with COVID-19 …

Predicting COVID-19 booster immunogenicity against future SARS-CoV-2 variants and the benefits of vaccine updates

D Cromer, A Reynaldi, A Mitchell, TE Schlub… - Nature …, 2024 - nature.com
The ongoing evolution of the SARS-CoV-2 virus has led to a move to update vaccine
antigens in 2022 and 2023. These updated antigens were chosen and approved based …

Safety and immunogenicity of Ad5-nCoV immunization after three-dose priming with inactivated SARS-CoV-2 vaccine in Chinese adults

H Zhang, N Xu, Y Xu, P Qin, R Dai, B Xu… - Nature …, 2023 - nature.com
Data on the safety and immunity of a heterologous booster (fourth dose) after three-doses of
inactivated SARS-CoV-2 vaccine in Chinese adults are limited. We evaluate the safety and …

Long-term systemic and mucosal SARS-CoV-2 IgA response and its association with persistent smell and taste disorders

J Denis, A Garnier, L Cheutin, A Ferrier… - Frontiers in …, 2023 - frontiersin.org
Introduction Current approved COVID-19 vaccines, notably mRNA and adenoviral vectored
technologies, still fail to fully protect against infection and transmission of various SARS-CoV …

Effect of homologous or heterologous vaccine booster over two initial doses of inactivated COVID-19 vaccine

V Luvira, P Pitisuttithum - Expert Review of Vaccines, 2024 - Taylor & Francis
Introduction Inactivated vaccines were delivered to low-and middle-income countries during
the early pandemics of COVID-19. Currently, more than 10 inactivated COVID-19 vaccines …

Heterologous booster vaccination enhances antibody responses to SARS-CoV-2 by improving Tfh function and increasing B-cell clonotype SHM frequency

Y Song, J Wang, Z Yang, Q He, C Bao, Y ** a mucosal vaccine against SARS-CoV-2 is critical for combatting the epidemic.
Here, we investigated long-term immune responses and protection against SARS-CoV-2 for …

Non-spike and spike-specific memory T cell responses after the third dose of inactivated COVID-19 vaccine

R Huang, L Ying, J Wang, J **a, Y Zhang… - Frontiers in …, 2023 - frontiersin.org
Background During the COVID-19 epidemic, vaccination has become the most safe and
effective way to prevent severe illness and death. Inactivated vaccines are the most widely …