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The dawn of spatial omics
D Bressan, G Battistoni, GJ Hannon - Science, 2023 - science.org
Spatial omics has been widely heralded as the new frontier in life sciences. This term
encompasses a wide range of techniques that promise to transform many areas of biology …
encompasses a wide range of techniques that promise to transform many areas of biology …
To metabolomics and beyond: a technological portfolio to investigate cancer metabolism
F Danzi, R Pacchiana, A Mafficini, MT Scupoli… - … and Targeted Therapy, 2023 - nature.com
Tumour cells have exquisite flexibility in reprogramming their metabolism in order to support
tumour initiation, progression, metastasis and resistance to therapies. These reprogrammed …
tumour initiation, progression, metastasis and resistance to therapies. These reprogrammed …
Multi-omics single-cell data integration and regulatory inference with graph-linked embedding
ZJ Cao, G Gao - Nature Biotechnology, 2022 - nature.com
Despite the emergence of experimental methods for simultaneous measurement of multiple
omics modalities in single cells, most single-cell datasets include only one modality. A major …
omics modalities in single cells, most single-cell datasets include only one modality. A major …
Inductively coupled plasma mass spectrometry
T Van Acker, S Theiner, E Bolea-Fernandez… - Nature Reviews …, 2023 - nature.com
Inductively coupled plasma mass spectrometry (ICP-MS) combines plasma chemistry, which
produces singly charged elemental ions, with mass spectrometric detection. Unlike other …
produces singly charged elemental ions, with mass spectrometric detection. Unlike other …
T cell subsets and functions in atherosclerosis
Atherosclerosis is a chronic inflammatory disease of the arterial wall and the primary
underlying cause of cardiovascular disease. Data from in vivo imaging, cell-lineage tracing …
underlying cause of cardiovascular disease. Data from in vivo imaging, cell-lineage tracing …
[HTML][HTML] Determinants of resident tissue macrophage identity and function
C Blériot, S Chakarov, F Ginhoux - Immunity, 2020 - cell.com
Resident tissue macrophages (RTMs) have a broad spectrum of immune-and non-immune-
related tissue-supporting activities. The roots of this heterogeneity and versatility are only …
related tissue-supporting activities. The roots of this heterogeneity and versatility are only …
Streamlined single-cell proteomics by an integrated microfluidic chip and data-independent acquisition mass spectrometry
ST Gebreyesus, AA Siyal, RB Kitata, ESW Chen… - Nature …, 2022 - nature.com
Single-cell proteomics can reveal cellular phenotypic heterogeneity and cell-specific
functional networks underlying biological processes. Here, we present a streamlined …
functional networks underlying biological processes. Here, we present a streamlined …
Microfluidic impedance cytometry enabled one‐step sample preparation for efficient single‐cell mass spectrometry
Single‐cell mass spectrometry (MS) is significant in biochemical analysis and holds great
potential in biomedical applications. Efficient sample preparation like sorting (ie, separating …
potential in biomedical applications. Efficient sample preparation like sorting (ie, separating …
OMIP‐069: forty‐color full spectrum flow cytometry panel for deep immunophenoty** of major cell subsets in human peripheral blood
LM Park, J Lannigan, MC Jaimes - Cytometry Part A, 2020 - Wiley Online Library
PURPOSE AND APPROPRIATE SAMPLE TYPES This 40‐color flow cytometry‐based panel
was developed for in‐depth immunophenoty** of the major cell subsets present in human …
was developed for in‐depth immunophenoty** of the major cell subsets present in human …
T cell dysfunction in cancer
DS Thommen, TN Schumacher - Cancer cell, 2018 - cell.com
Therapeutic reinvigoration of tumor-specific T cells has greatly improved clinical outcome in
cancer. Nevertheless, many patients still do not achieve durable benefit. Recent evidence …
cancer. Nevertheless, many patients still do not achieve durable benefit. Recent evidence …