Bradykinesia is one of the cardinal motor symptoms of Parkinson's disease and other
parkinsonisms. The various clinical aspects related to bradykinesia and the …

Pathologies characteristic of Alzheimer's disease (ie, hyperphosphorylated tau and amyloid-
β (Aβ) plaques), cardiovascular disease, and limbic predominant TDP-43 encephalopathy …

Mild cognitive changes, including executive dysfunction, are seen in Parkinson's Disease
(PD). Approximately 30% of individuals with PD develop Parkinson's disease dementia …

White matter damage quantified as white matter hyperintensities (WMH) may aggravate
cognitive and motor impairments, but whether and how WMH burden impacts these …

Clinical manifestations and evolution are very heterogeneous among individuals with
Parkinson's disease (PD). The aims of this study were to investigate the pattern of …

Objective This study aimed to develop an automatic classifier to distinguish different motor
subtypes of Parkinson's disease (PD) based on multilevel indices of resting-state functional …

There are limited data on vascular, inflammatory, metabolic risk factors of dementia in
Parkinson's disease (PD) with type 2 diabetes mellitus (DM)(PD-DM). In a study of 928 …

Introduction Previous studies have found associations between grey matter atrophy and
white matter hyperintensities (WMH) of vascular origin with cognitive and motor deficits in …

Background Excessive aggregation of α-synuclein is the key pathophysiological feature of
Parkinson's disease (PD). Rapid eye movement sleep behavior disorder (RBD) is also …

The relationship between cerebrovascular disease and parkinsonism is commonly seen in
everyday clinical practice but remains ill-defined and under-recognised with little guidance …