Late-stage retinal degenerative disease involving photoreceptor loss can be treated by
optogenetic therapy, cell transplantation and retinal prostheses. These approaches aim to …

Photoreceptors (PRs), as the most abundant and light-sensing cells of the neuroretina, are
responsible for converting light into electrical signals that can be interpreted by the brain. PR …

Inherited or acquired photoreceptor degenerations, one of the leading causes of irreversible
blindness in the world, are a group of retinal disorders that initially affect rods and cones …

The tightly structured neural retina has a unique vascular network comprised of three
interconnected plexuses in the inner retina (and choroid for outer retina), which provide …

Retinal neurodegeneration can impair visual perception at different levels, involving not only
photoreceptors, which are the most metabolically active cells, but also the inner retina …

To further improve the quality of visual percepts elicited by microelectronic retinal
prosthetics, substantial efforts have been made to understand how retinal neurons respond …

We have determined the impact of rod death and cone reorganization on the spatiotemporal
receptive fields (RFs) and spontaneous activity of distinct retinal ganglion cell (RGC) types …

The aim of this study was to examine changes in photoreceptor ellipsoid zone (EZ) and
postreceptor retinal layer in retinitis pigmentosa (RP) patients by ganglion cell analysis …

The group of retinal degenerations, retinitis pigmentosa (RP), comprises more than 150
genetic abnormalities affecting photoreceptors. Finding degenerative pathways common to …

Purpose: To study the disease course of RPE65-associated inherited retinal degenerations
(IRDs) as a function of the genotype, define a critical age for blindness, and identify potential …