Cannabis and synaptic reprogramming of the develo** brain

A Bara, JMN Ferland, G Rompala, H Szutorisz… - Nature Reviews …, 2021 - nature.com
Recent years have been transformational in regard to the perception of the health risks and
benefits of cannabis with increased acceptance of use. This has unintended …

THC and CBD: Similarities and differences between siblings

N Stella - Neuron, 2023 - cell.com
Summary Δ 9-tetrahydrocannabinol (THC) and its sibling, cannabidiol (CBD), are produced
by the same Cannabis plant and have similar chemical structures but differ dramatically in …

Cannabis and the develo** brain: insights into its long-lasting effects

YL Hurd, OJ Manzoni, CCW Lim, T Sun, J Leung, JYC Chung… - JAMA …, 2022 - jamanetwork.com
Importance Va** products were initially designed to deliver nicotine as a tobacco cigarette
substitute (eg, electronic cigarettes) but are now frequently used to deliver psychoactive …

Evidence for the risks and consequences of adolescent cannabis exposure

A Levine, K Clemenza, M Rynn, J Lieberman - Journal of the American …, 2017 - Elsevier
Objective This review of the scientific literature examines the potential adult sequelae of
exposure to cannabis and related synthetic cannabinoids in adolescence. We examine the …

Adolescent drug exposure: A review of evidence for the development of persistent changes in brain function

H Salmanzadeh, SM Ahmadi-Soleimani… - Brain research …, 2020 - Elsevier
Over the past decade, many studies have indicated that adolescence is a critical period of
brain development and maturation. The refinement and maturation of the central nervous …

The role of the endocannabinoid system and genetic variation in adolescent brain development

HC Meyer, FS Lee, DG Gee - Neuropsychopharmacology, 2018 - nature.com
During adolescence, both rodent and human studies have revealed dynamic changes in the
developmental trajectories of corticolimbic structures, which are known to contribute to the …

Adolescent neurodevelopment and vulnerability to psychosis

PK Patel, LD Leathem, DL Currin, KH Karlsgodt - Biological Psychiatry, 2021 - Elsevier
Adolescence is characterized by significant changes in several domains, including brain
structure and function, puberty, and social and environmental factors. Some of these …

Amphetamine disrupts dopamine axon growth in adolescence by a sex-specific mechanism in mice

LM Reynolds, G Hernandez, D MacGowan… - Nature …, 2023 - nature.com
Initiating drug use during adolescence increases the risk of develo** addiction or other
psychopathologies later in life, with long-term outcomes varying according to sex and exact …

Adolescent neurodevelopment and substance use: Receptor expression and behavioral consequences

HHA Thorpe, S Hamidullah, BW Jenkins… - Pharmacology & …, 2020 - Elsevier
Adolescence is the transitional period between childhood and adulthood, during which
extensive brain development occurs. Since this period also overlaps with the initiation of …