Cancer radio-immunotherapy, integrating external/internal radiation therapy with immuno-
oncology treatments, emerges in the current management of cancer. A growing number of …

In cancer treatment, traditional radiotherapy (RT) is routinely conducted in local tumors and
limited by radioresistance, while recently emerged immunotherapy is confronted with low …

Hypoxia, as a characteristic feature of solid tumors, has a close relationship with tumor
resistance to photodynamic therapy (PDT) and chemotherapy. Perfluorocarbon (PFC) is …

It is highly desirable yet significantly challenging to fabricate injectable, self‐crosslinked, self‐
fused, and antifouling polyzwitterionic hydrogels, whose successful preparation will expand …

Bacterial‐based delivery strategies have recently emerged as a unique research direction in
the field of drug delivery. However, bacterial vectors are quickly phagocytosed by immune …

Every stage of cancer metastasis, immune surveillance evasion, and therapeutic resistance
is influenced by tumor microenvironment (TME). In light of this, nanomedicines design based …

Hypoxia-inducible factor-1α (HIF-1α) is a primary metabolic sensor, and is expressed in
different immune cells, such as macrophage, dendritic cell, neutrophil, T cell, and non …

Mutation burden, hypoxia, and immunoediting contribute to altered metabolic profiles in
tumor cells, resulting in a tumor microenvironment (TME) characterized by accumulation of …

The therapy of solid tumors is always hampered by the intrinsic tumor physical
microenvironment (TPME) featured with compact and rigid extracellular matrix (ECM) …

Radiotherapy (RT) plays an important role in tumor therapy due to its noninvasiveness and
wide adaptation. In recent years, radiation therapy has been discovered to induce an anti …