Addiction, dopamine, and the molecular mechanisms of memory

JD Berke, SE Hyman - Neuron, 2000 - cell.com
Joshua D. Berke* § and Steven E. Hyman*†‡* Section on Molecular Plasticity National
Institute of Neurological Disorders and Stroke locomotor activity. Psychostimulants also tend …

The pharmacology and clinical pharmacology of 3, 4-methylenedioxymethamphetamine (MDMA,“ecstasy”)

AR Green, AO Mechan, JM Elliott, E O'Shea… - Pharmacological …, 2003 - Elsevier
Abstract The amphetamine derivative (±)-3, 4-methylenedioxymethamphetamine (MDMA,
ecstasy) is a popular recreational drug among young people, particularly those involved in …

[PDF][PDF] Specificity in the cAMP/PKA signaling pathway. Differential expression, regulation, and subcellular localization of subunits of PKA

BS Skalhegg, K Tasken - Front Biosci, 2000 - researchgate.net
SPECIFICITY IN THE cAMP/PKA SIGNALING PATHWAY. DIFFERENTIAL EXPRESSION,
REGULATION, AND SUBCELLULAR LOCALIZATION OF SUBUNITS OF Page 1 [Frontiers in …

Cyclic nucleotide-dependent protein kinases: intracellular receptors for cAMP and cGMP action

SH Francis, JD Corbin - Critical reviews in clinical laboratory …, 1999 - Taylor & Francis
Intracellular cAMP and cGMP levels are increased in response to a variety of hormonal and
chemical stimuli; these nucleotides play key roles as second messenger signals in …

Inhibition of the striatum-enriched phosphodiesterase PDE10A: a novel approach to the treatment of psychosis

JA Siuciak, DS Chapin, JF Harms, LA Lebel… - …, 2006 - Elsevier
Phosphodiesterase 10A (PDE10A) is a recently identified cyclic nucleotide
phosphodiesterase expressed primarily in dopaminoreceptive medium spiny neurons of the …

The biological functions of A-kinase anchor proteins

A Feliciello, ME Gottesman, EV Avvedimento - Journal of molecular biology, 2001 - Elsevier
cAMP-dependent protein kinase is targeted to discrete subcellular locations by a family of
specific anchor proteins (A-kinase anchor proteins, AKAPs). Localization recruits protein …

Impaired growth and fertility of cAMP-specific phosphodiesterase PDE4D-deficient mice

SLC **, FJ Richard, WP Kuo… - Proceedings of the …, 1999 - National Acad Sciences
In eukaryotic cells, the inactivation of the cyclic nucleotide signal depends on a complex
array of cyclic nucleotide phosphodiesterases (PDEs). Although it has been established that …

Minireview: PRKAR1A: Normal and Abnormal Functions

I Bossis, CA Stratakis - Endocrinology, 2004 - academic.oup.com
The type 1α regulatory subunit (RIα) of cAMP-dependent protein kinase (PKA)(coded by the
PRKAR1A gene) is the main component of type I PKA, which regulates most of the serine …

Antipsychotic drugs and neuroplasticity: insights into the treatment and neurobiology of schizophrenia

C Konradi, S Heckers - Biological psychiatry, 2001 - Elsevier
This paper reviews the evidence that antipsychotic drugs induce neuroplasticity. We outline
how the synaptic changes induced by the antipsychotic drug haloperidol may help our …

[引用][C] Molecular mechanisms and therapeutical implications of intramembrane receptor/receptor interactions among heptahelical receptors with examples from the …

LF Agnati, S Ferré, C Lluis, R Franco, K Fuxe - Pharmacological reviews, 2003 - ASPET