Anatomy of teleost fish immune structures and organs

H Bjørgen, EO Koppang - Principles of Fish Immunology: From Cells and …, 2022 - Springer
The understanding of the functions of the immune system needs a fundament of solid
anatomical knowledge. The construction and arrangement of the different components of the …

A cold-blooded view of adaptive immunity

MF Flajnik - Nature Reviews Immunology, 2018 - nature.com
The adaptive immune system arose 500 million years ago in ectothermic (cold-blooded)
vertebrates. Classically, the adaptive immune system has been defined by the presence of …

[PDF][PDF] De novo assembly of 20 chicken genomes reveals the undetectable phenomenon for thousands of core genes on microchromosomes and subtelomeric regions

M Li, C Sun, N Xu, P Bian, X Tian… - Molecular biology …, 2022 - academic.oup.com
The gene numbers and evolutionary rates of birds were assumed to be much lower than
those of mammals, which is in sharp contrast to the huge species number and …

B lymphocytes: how they develop and function

TW LeBien, TF Tedder - Blood, The Journal of the American …, 2008 - ashpublications.org
The discovery that lymphocyte subpopulations participate in distinct components of the
immune response focused attention onto the origins and function of lymphocytes more than …

Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution

Project management: Fulton Lucinda A. 1 Mardis … - Nature, 2004 - nature.com
We present here a draft genome sequence of the red jungle fowl, Gallus gallus. Because the
chicken is a modern descendant of the dinosaurs and the first non-mammalian amniote to …

Clonal selection and learning in the antibody system

K Rajewsky - Nature, 1996 - nature.com
Each antibody-producing B cell makes antibodies of unique specificity, reflecting a series of
ordered gene rearrangements which must be successfully performed if the cell is to survive …

Development of immune checkpoint therapy for cancer

JM Fritz, MJ Lenardo - Journal of Experimental Medicine, 2019 - rupress.org
Since the early 20th century, immunologists have investigated mechanisms that protect
vertebrates from damaging immune responses against self-antigens by mature lymphocytes …

The early history of B cells

MD Cooper - Nature Reviews Immunology, 2015 - nature.com
The separate development of functionally intertwined lineages of lymphocytes known as B
cells and T cells is now recognized as a fundamental organizing principle of the adaptive …

Immunology's coming of age

SHE Kaufmann - Frontiers in immunology, 2019 - frontiersin.org
This treatise describes the development of immunology as a scientific discipline with a focus
on its foundation. Toward the end of the nineteenth century, the study of immunology was …

Metabolism of immunoglobulins

TA Waldmann, W Strober, RM BLAESE - Progress in immunology, 1971 - Elsevier
Publisher Summary This chapter examines the metabolism of immunoglobulins. Turnover
studies with purified radioiodinated immunoglobulin molecules have allowed the definition …