Molecular regulations of circadian rhythm and implications for physiology and diseases
The term “circadian rhythms” describes endogenous oscillations with ca. 24-h period
associated with the earth's daily rotation and light/dark cycle. Such rhythms reflect the …
associated with the earth's daily rotation and light/dark cycle. Such rhythms reflect the …
The functional and clinical significance of the 24-hour rhythm of circulating glucocorticoids
Adrenal glucocorticoids are major modulators of multiple functions, including energy
metabolism, stress responses, immunity, and cognition. The endogenous secretion of …
metabolism, stress responses, immunity, and cognition. The endogenous secretion of …
Stress & sleep: A relationship lasting a lifetime
Stress is an adaptative response aimed at restoring body homeostasis. The classical
neuroendocrine stress response involving the activation of the hypothalamic-pituitary …
neuroendocrine stress response involving the activation of the hypothalamic-pituitary …
New insights into the circadian rhythm and its related diseases
Y **e, Q Tang, G Chen, M **e, S Yu, J Zhao… - Frontiers in …, 2019 - frontiersin.org
Circadian rhythms (CR) are a series of endogenous autonomous oscillators generated by
the molecular circadian clock which acting on coordinating internal time with the external …
the molecular circadian clock which acting on coordinating internal time with the external …
[HTML][HTML] Stress: endocrine physiology and pathophysiology
Stress constitutes a state of threatened homeostasis triggered by intrinsic or extrinsic
adverse forces (stressors) and is counteracted by an intricate repertoire of physiologic and …
adverse forces (stressors) and is counteracted by an intricate repertoire of physiologic and …
Circadian rhythms, time-restricted feeding, and healthy aging
Circadian rhythms optimize physiology and health by temporally coordinating cellular
function, tissue function, and behavior. These endogenous rhythms dampen with age and …
function, tissue function, and behavior. These endogenous rhythms dampen with age and …
[HTML][HTML] Timing matters: the interplay between early mealtime, circadian rhythms, gene expression, circadian hormones, and metabolism—a narrative review
Achieving synchronization between the central and peripheral body clocks is essential for
ensuring optimal metabolic function. Meal timing is an emerging field of research that …
ensuring optimal metabolic function. Meal timing is an emerging field of research that …
Central and peripheral circadian clocks in mammals
JA Mohawk, CB Green… - Annual review of …, 2012 - annualreviews.org
The circadian system of mammals is composed of a hierarchy of oscillators that function at
the cellular, tissue, and systems levels. A common molecular mechanism underlies the cell …
the cellular, tissue, and systems levels. A common molecular mechanism underlies the cell …
Circadian clocks of the kidney: function, mechanism, and regulation
HM Costello, JG Johnston, A Juffre… - Physiological …, 2022 - journals.physiology.org
An intrinsic cellular circadian clock is located in nearly every cell of the body. The peripheral
circadian clocks within the cells of the kidney contribute to the regulation of a variety of renal …
circadian clocks within the cells of the kidney contribute to the regulation of a variety of renal …
[HTML][HTML] The mammalian circadian clock and its entrainment by stress and exercise
The mammalian circadian clock regulates day–night fluctuations in various physiological
processes. The circadian clock consists of the central clock in the suprachiasmatic nucleus …
processes. The circadian clock consists of the central clock in the suprachiasmatic nucleus …