Fluorescent nanoparticles for super-resolution imaging

W Li, GS Kaminski Schierle, B Lei, Y Liu… - Chemical …, 2022 - ACS Publications
Super-resolution imaging techniques that overcome the diffraction limit of light have gained
wide popularity for visualizing cellular structures with nanometric resolution. Following the …

Xanthene, cyanine, oxazine and BODIPY: the four pillars of the fluorophore empire for super-resolution bioimaging

S Samanta, K Lai, F Wu, Y Liu, S Cai, X Yang… - Chemical Society …, 2023 - pubs.rsc.org
In the realm of biological research, the invention of super-resolution microscopy (SRM) has
enabled the visualization of ultrafine sub-cellular structures and their functions in live cells at …

Understanding 3D genome organization by multidisciplinary methods

I Jerkovic, G Cavalli - Nature reviews Molecular cell biology, 2021 - nature.com
Understanding how chromatin is folded in the nucleus is fundamental to understanding its
function. Although 3D genome organization has been historically difficult to study owing to a …

Organ-on-chip models for infectious disease research

R Alonso-Roman, AS Mosig, MT Figge… - Nature …, 2024 - nature.com
Research on microbial pathogens has traditionally relied on animal and cell culture models
to mimic infection processes in the host. Over recent years, developments in microfluidics …

Single multimode fibre for in vivo light-field-encoded endoscopic imaging

Z Wen, Z Dong, Q Deng, C Pang, CF Kaminski, X Xu… - Nature …, 2023 - nature.com
Super-resolution microscopy is typically not applicable to in situ imaging through a narrow
channel due to the requirement for complex optics. Although multimode fibres (MMFs) have …

MINFLUX nanometer-scale 3D imaging and microsecond-range tracking on a common fluorescence microscope

R Schmidt, T Weihs, CA Wurm, I Jansen… - Nature …, 2021 - nature.com
The recently introduced minimal photon fluxes (MINFLUX) concept pushed the resolution of
fluorescence microscopy to molecular dimensions. Initial demonstrations relied on custom …

Super-resolution microscopy demystified

L Schermelleh, A Ferrand, T Huser, C Eggeling… - Nature cell …, 2019 - nature.com
Super-resolution microscopy (SRM) bypasses the diffraction limit, a physical barrier that
restricts the optical resolution to roughly 250 nm and was previously thought to be …

FRET as a biomolecular research tool—understanding its potential while avoiding pitfalls

WR Algar, N Hildebrandt, SS Vogel, IL Medintz - Nature methods, 2019 - nature.com
The applications of Förster resonance energy transfer (FRET) grow with each year.
However, different FRET techniques are not applied consistently, nor are results uniformly …

Nanoparticle characterization: what to measure?

MM Modena, B Rühle, TP Burg, S Wuttke - Advanced Materials, 2019 - Wiley Online Library
What to measure? is a key question in nanoscience, and it is not straightforward to address
as different physicochemical properties define a nanoparticle sample. Most prominent …

Roadmap on label‐free super‐resolution imaging

VN Astratov, YB Sahel, YC Eldar… - Laser & photonics …, 2023 - Wiley Online Library
Label‐free super‐resolution (LFSR) imaging relies on light‐scattering processes in
nanoscale objects without a need for fluorescent (FL) staining required in super‐resolved FL …