Tyrosinase is a multi-copper enzyme which is widely distributed in different organisms and
plays an important role in the melanogenesis and enzymatic browning. Therefore, its …

Tyrosinase is a key enzyme target to design new chemical ligands against melanogenesis.
In the current review, different chemical derivatives are explored which have been used as …

The incidence of 2019 novel corona virus (SARS-CoV-2) has created a medical emergency
throughout the world. Various efforts have been made to develop the vaccine or effective …

A new series of bis-benzimidazole clubbed with primary amine (3i-iii) and aromatic
aldehydes (4i-ix) were design and synthesize with an intention to search an anticancer lead …

In this study we have performed the in vitro anticancer activity of spiro oxindole derivatives
against MCF-7 (human Adreno carcinoma) and MDA-MB-231 (triple negative breast cancer) …

Asthma patients may increase their susceptibility to SARS-CoV-2 infection and the poor
prognosis of coronavirus disease 2019 (COVID-19). However, anti-COVID-19/asthma …

Human tyrosinase (hTYR) is a key and rate-limiting enzyme along with human tyrosinase-
related protein-1 (hTYRP1), which are among the most prominent targets of inhibiting hyper …

Tyrosinase, a rate-limiting enzyme for melanin production, has been the most efficient target
for the development of depigmenting agents. Although hydroquinone, kojic acid, and arbutin …

Abstract In this study, novel 1, 2, 3-triazole compounds containing carbasugar frameworks (5
and 6) were synthesized by the copper-catalyzed azide-alkyne cycloaddition reactions and …

The design of novel inhibitors to target BACE1 with reduced cytotoxicity effects is a
promising approach to treat Alzheimer's disease (AD). Multiple clinical drugs and antibodies …