The regulation of the pleiotropic transcription factor, nuclear factor-κB (NF-κB) by miRNAs
and proteins is extensively studied. More recently, the NF-κB signaling was also reported to …

Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), a well-known lncRNA
associated with numerous diseases, particularly cancer, has received increased attention …

MALAT 1 is a conserved long noncoding RNA whose expression correlates with many
human cancers. However, its significance in immunity remains largely unknown. Here, we …

The interferon-induced proteins with tetratricopeptide repeats (IFITs) are a family of antiviral
proteins conserved throughout all vertebrates. IFIT1 binds tightly to non-self RNA …

Background: Drug-Target Interactions (DTI) play a crucial role in discovering new drug
candidates and finding new proteins to target for drug development. Although the number of …

The nuclear factor‐κB (NF‐κB) family of transcription factors play an essential role for the
regulation of inflammatory responses, immune function and malignant transformation …

Background The airway epithelial cell plays a central role in coordinating the pulmonary
response to injury and inflammation. Here, transforming growth factor-β (TGFβ) activates …

Inducible transcriptional elongation is a rapid, stereotypic mechanism for activating
immediate early immune defense genes by the epithelium in response to viral pathogens …

Mucosal surfaces of the human body are lined by a contiguous epithelial cell surface that
forms a barrier to aerosolized pathogens. Specialized pattern recognition receptors detect …

Respiratory syncytial virus infection is responsible for seasonal upper and lower respiratory
tract infections worldwide, causing substantial morbidity. Self-inoculation of the virus into the …