[HTML][HTML] Enteric coating of tablets containing an amorphous solid dispersion of an enteric polymer and a weakly basic drug: a strategy to enhance in vitro release
Recent work has highlighted that amorphous solid dispersions (ASDs) containing
delamanid (DLM) and an enteric polymer, hypromellose phthalate (HPMCP), appear to be …
delamanid (DLM) and an enteric polymer, hypromellose phthalate (HPMCP), appear to be …
The importance of surface composition and wettability on the dissolution performance of high drug loading amorphous dispersion formulations
One of the limitations with an amorphous solid dispersion (ASD) formulation strategy is low
drug loading. Hydrophobic drugs have poor wettability and require a substantial amount of …
drug loading. Hydrophobic drugs have poor wettability and require a substantial amount of …
Surface Solid Dispersion of Ketoconazole on Trehalose Dihydrate using Spray Drying to Achieve Enhanced Dissolution Rate
W Weecharangsan, RJ Lee - AAPS PharmSciTech, 2024 - Springer
Ketoconazole (K) is a poorly water-soluble drug that faces significant challenges in
achieving therapeutic efficacy. This study aimed to enhance the dissolution rate of …
achieving therapeutic efficacy. This study aimed to enhance the dissolution rate of …
A Commentary on Co-Processed API as a Promising Approach to Improve Sustainability for the Pharmaceutical Industry
Pharmaceutical products represent a meaningful target for sustainability improvement and
emissions reduction. It is proposed here that rethinking the standard, and often linear …
emissions reduction. It is proposed here that rethinking the standard, and often linear …
[HTML][HTML] Trends in amorphous solid dispersion drug products approved by the US Food and Drug Administration between 2012 and 2023
Abstract Forty-eight (48) drug products (DPs) containing amorphous solid dispersions
(ASDs) have been approved by the US Food and Drug Administration in the 12-year period …
(ASDs) have been approved by the US Food and Drug Administration in the 12-year period …
Impact of route of particle engineering on dissolution performance of posaconazole
Even when they have similar particle size, micron sized drug crystals prepared via different
process routes may still exhibit considerable variability in pharmaceutical properties, due to …
process routes may still exhibit considerable variability in pharmaceutical properties, due to …
Neat Amorphous Form and Amorphous Solid Dispersions of Apalutamide: A Comparative Study
R Sapkal, P Devangan, J Madan… - Journal of Drug Delivery …, 2025 - Elsevier
Amorphous form and Amorphous solid dispersions (ASDs) of an anticancer drug
Apalutamide (APA) with four polymers of different categories namely, PVPK30, HPMCAS …
Apalutamide (APA) with four polymers of different categories namely, PVPK30, HPMCAS …
Regulatory Considerations for Stability Studies of Co-Processed Active Pharmaceutical Ingredient
RK Orr, T Rawalpally, LS Gorka, LR Bonaga… - The AAPS Journal, 2024 - Springer
A co-processed active pharmaceutical ingredient (CP API) is the combination of an active
pharmaceutical ingredient (API) with non-active component (s). This technology has been …
pharmaceutical ingredient (API) with non-active component (s). This technology has been …
Professor Lynne S. Taylor: Scientist, educator, and adventurer
This special edition of the Journal of Pharmaceutical Sciences is dedicated to Professor
Lynne S. Taylor (Retter Distinguished Professor of Pharmacy, Department of Industrial and …
Lynne S. Taylor (Retter Distinguished Professor of Pharmacy, Department of Industrial and …