The past decade has seen significant advances in our understanding of Hedgehog (HH)
signaling pathway in various biological events. HH signaling pathway exerts its biological …

Simple Summary The Hedgehog/GLI (Hh/GLI) pathway plays a major role during
development and it is commonly dysregulated in many diseases, including cancer. This …

The Hedgehog (Hh) family of proteins control cell growth, survival, and fate, and pattern
almost every aspect of the vertebrate body plan. The use of a single morphogen for such a …

The mammary gland is a compound, branched tubuloalveolar structure and a major
characteristic of mammals. The mammary gland has evolved from epidermal apocrine …

Basal cell carcinomas (BCCs) were essentially a molecular'black box'until some 12 years
ago, when identification of a genetic flaw in a rare subset of patients who have a great …

The hedgehog (HH) signaling pathway regulates normal cell growth and differentiation. As a
consequence of improper control, aberrant HH signaling results in tumorigenesis and …

The Hedgehog (Hh) pathway is a major regulator of many fundamental processes in
vertebrate embryonic development including stem cell maintenance, cell differentiation …

The Hedgehog family of secreted morphogenetic proteins acts through a complex
evolutionary conserved signaling pathway to regulate patterning events during development …

The hedgehog (Hh) pathway is a sophisticated conserved cell signaling pathway that plays
an essential role in controlling cell specification and proliferation, survival factors, and tissue …

Abstract FOXM1 (Forkhead box M1) is a typical proliferation-associated transcription factor,
which stimulates cell proliferation and exhibits a proliferation-specific expression pattern …