Overcoming immune evasion in melanoma

K Eddy, S Chen - International journal of molecular sciences, 2020 - mdpi.com
Melanoma is the most aggressive and dangerous form of skin cancer that develops from
transformed melanocytes. It is crucial to identify melanoma at its early stages, in situ, as it is …

Melanoma

D Schadendorf, DE Fisher, C Garbe… - Nature reviews Disease …, 2015 - nature.com
Melanoma is a common cancer in the Western world with an increasing incidence. Sun
exposure is still considered to be the major risk factor for melanoma. The prognosis of …

Global burden of cutaneous melanoma in 2020 and projections to 2040

M Arnold, D Singh, M Laversanne, J Vignat… - JAMA …, 2022 - jamanetwork.com
Importance Despite many cases being preventable, cutaneous melanoma remains the most
serious skin cancer worldwide. Understanding the scale and profile of the disease is vital to …

Risk factors and innovations in risk assessment for melanoma, basal cell carcinoma, and squamous cell carcinoma

K Wunderlich, M Suppa, S Gandini, J Lipski, JM White… - Cancers, 2024 - mdpi.com
Simple Summary Skin cancer is a common, preventable condition of global importance.
Different types of skin cancer, like melanoma, basal cell carcinoma, and squamous cell …

[HTML][HTML] A practice guideline from the American College of Medical Genetics and Genomics and the National Society of Genetic Counselors: referral indications for …

H Hampel, RL Bennett, A Buchanan, R Pearlman… - Genetics in …, 2015 - Elsevier
Disclaimer: The practice guidelines of the American College of Medical Genetics and
Genomics (ACMG) and the National Society of Genetic Counselors (NSGC) are developed …

The molecular pathology of melanoma: an integrated taxonomy of melanocytic neoplasia

BC Bastian - Annual Review of Pathology: Mechanisms of …, 2014 - annualreviews.org
Melanomas comprise multiple biologically distinct categories, which differ in cell of origin,
age of onset, clinical and histologic presentation, pattern of metastasis, ethnic distribution …

Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer

AP Klein, BM Wolpin, HA Risch… - Nature …, 2018 - nature.com
Abstract In 2020, 146,063 deaths due to pancreatic cancer are estimated to occur in Europe
and the United States combined. To identify common susceptibility alleles, we performed the …

Pancreatic ductal adenocarcinoma: risk factors, screening, and early detection

AE Becker, YG Hernandez, H Frucht… - World journal of …, 2014 - pmc.ncbi.nlm.nih.gov
Pancreatic cancer is the fourth most common cause of cancer-related deaths in the United
States, with over 38000 deaths in 2013. The opportunity to detect pancreatic cancer while it …

Comparative genomics provides etiologic and biological insight into melanoma subtypes

F Newell, PA Johansson, JS Wilmott, K Nones… - Cancer …, 2022 - aacrjournals.org
Melanoma is a cancer of melanocytes, with multiple subtypes based on body site location.
Cutaneous melanoma is associated with skin exposed to ultraviolet radiation; uveal …

Hereditary melanoma: Update on syndromes and management: Genetics of familial atypical multiple mole melanoma syndrome

E Soura, PJ Eliades, K Shannon, AJ Stratigos… - Journal of the American …, 2016 - Elsevier
Malignant melanoma is considered the most lethal skin cancer if it is not detected and
treated during its early stages. About 10% of melanoma patients report a family history of …