Guanine-rich DNA sequences have the propensity to adopt four-stranded tetrahelical G-
quadruplex (G4) structures that are overrepresented in gene promoters. The structural …

Guanine and related nucleobases such as guanosine, deoxyguanosine and isoguanosine
are notable molecular tools for designing functional supramolecular assemblies. This …

Abstract G-quadruplex (G4) with stacked G-tetrads structure is able to bind hemin (iron (III)-
protoporphyrin IX) to form a unique type of DNAzyme/RNAzyme with peroxidase-mimicking …

Visualization of DNA and RNA quadruplex formation in human cells was demonstrated
recently with different quadruplex-specific antibodies. Despite the significant interest in these …

Biomimetic enzymes have emerged as ideal alternatives to natural enzymes, and there is
considerable interest in designing biomimetic enzymes with enhanced catalytic performance …

The present paper reviews the recent advances in and applications of experimental
techniques used to study interactions between G-quadruplex structures and ligands that are …

Since the initial discovery of the catalytic capability of short DNA fragments, this peculiar
enzyme-like property (termed DNAzyme) has continued to garner much interest in the …

Conspectus Biomimetics is defined as a “practice of making technological design that copies
natural processes”, with the idea that “nature has already solved the challenges we are …

Recent and unambiguous evidences of the formation of DNA and RNA G-quadruplexes in
cells has provided solid support for these structures to be considered as valuable targets in …

Guanine-rich DNA or RNA sequences can fold into higher-order, four-stranded structures
termed quadruplexes that are suspected to play pivotal roles in cellular mechanisms …