Natural killer (NK) cells contribute to the first line of defense against viruses and to the
control of tumor growth and metastasis spread. The discovery of HLA class I specific …

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Natural killer (NK) cells have roles in immunity and reproduction that are controlled by
variable receptors that recognize MHC class I molecules. The variable NK cell receptors …

Natural killer cells can discriminate between normal cells and cells that do not express
adequate amounts of major histocompatibility complex (MHC) class I molecules. The …

The fetus is considered to be an allograft that, paradoxically, survives pregnancy despite the
laws of classical transplantation immunology. There is no direct contact of the mother with …

MHC class I molecules are ligands for the killer-cell immunoglobulin-like receptors (KIRs),
which are expressed by natural killer cells and T cells. The interactions between these …

Killer-cell immunoglobulin-like receptor (KIR) genes form a diverse, immunogenetic system.
Group A and B KIR haplotypes have distinctive centromeric (Cen) and telomeric (Tel) gene …

Natural killer (NK) cells provide defense in the early stages of the innate immune response
against viral infections by producing cytokines and causing cytotoxicity 1. The killer …

Natural killer (NK) cells express inhibitory receptors for major histocompatibility complex
(MHC) class I antigens, preventing attack against healthy cells. Mouse cytomegalovirus …

KIR genes have evolved in primates to generate a diverse family of receptors with unique
structures that enable them to recognize MHC-class I molecules with locus and allele …