The anatomy and physiology of the microcirculation in human skin are complex. Normal
cutaneous microcirculation is organized in two parallel plexuses with capillary loops …

Cardiovascular disease (CVD) constitutes a leading worldwide health problem, with
increasing evidence of differences between women and men both in epidemiology …

Major depression represents a complex and prevalent psychological disease that is
characterized by persistent depressed mood, impaired cognitive function and complicated …

Depressive disorders can affect up to 350 million people worldwide, and in developed
countries, the percentage of patients with depressive disorders may be as high as 10 …

The endothelium is recognized to play an important role in various physiological functions
including vascular tone, permeability, anticoagulation, and angiogenesis. Endothelial …

Siraitia grosvenorii (SG) is an edible medicinal plant found mainly in Guangxi, China, and
Mogroside V (MGV) is the main component of SG extract. Previous research has shown that …

Background Growing evidence has shown that the antioxidant diet is a protective factor
against depression. However, the relationship between the Composite Dietary Antioxidant …

Oxidative stress (OS) is thought to play a role in mental disorders. However, it is not clear
whether the OS is the cause or consequence of the disorder. We investigated markers of …

Objective COVID-19 might cause neuroinflammation in the brain, which could decrease
neurocognitive function. We aimed to evaluate the causal associations and genetic overlap …

Major depressive disorder (MDD) is a very common, severe disease with a lifetime
prevalence of~ 10%. The pathogenesis of MDD is unknown and, unfortunately, therapy is …