Metabolomics is emerging as a promising tool to understand the effect of
immunometabolism for the development of novel host-directed alternative therapies …

The establishment of persistent infections and the reactivation of persistent bacteria to active
bacilli are the two hurdles in effective tuberculosis treatment. Mycobacterium tuberculosis …

Objective To investigate the characteristic of nasopharyngeal microbiota at different states of
Mycobacterium tuberculosis (MTB) infection. Methods Participants were recruited from a …

Tuberculosis remains the leading cause of death from a single pathogen. On the other hand,
antimicrobial resistance (AMR) makes it increasingly difficult to deal with this disease. We …

Background Diabetes mellitus (DM) is a major risk factor for tuberculosis (TB). Evidence has
linked the DM-related dysbiosis of gut microbiota to modifiable host immunity to …

Tuberculosis (TB) is defined as a chronic infection in both human and cattle hosts and many
subclinical cases remain undetected. After the pathogen is inhaled by a host, phagocyted …

Tuberculosis (TB) is one of the leading causes of human deaths worldwide caused by
infectious diseases. TB infection by Mycobacterium tuberculosis can occur in the lungs …

The microenvironment of the CNS (eye and brain) is fertile ground for infection if the barriers
are breached. The result of pathogen invasion is often devastating destruction of tissues. In …

Tuberculosis (TB) stands as the second most prevalent cause of global human mortality from
infectious diseases. In 2022, the World Health Organization documented an estimated …

Tuberculosis patients with diabetes, have higher sputum bacillary load, delayed sputum
conversion, higher rates of drug resistance, higher lung cavitary involvement and extra …