Oxidative stress (OS) is primarily caused by the formation of free radicals and reactive
oxygen species; it is considered as one of the prominent factors in slowing down and …

Responding to the increased popularity of herbal medicines and other forms of
complementary or alternative medicine world-wide, this reference reviews and evaluates …

Increasing evidence indicates that reactive oxygen species (ROS), consisting of superoxide,
hydrogen peroxide, and multiple others, do not only cause oxidative stress, but rather may …

Resveratrol, a constituent of red wine, has long been suspected to have cardioprotective
effects. Interest in this compound has been renewed in recent years, first from its …

The cofactor nicotinamide adenine dinucleotide (NAD+) has emerged as a key regulator of
metabolism, stress resistance and longevity. Apart from its role as an important redox carrier …

A number of small molecules with the ability to extend the lifespan of multiple organisms
have recently been discovered. Resveratrol, amongst the most prominent of these, has …

A progressive loss of neurons with age underlies a variety of debilitating neurological
disorders, including Alzheimer's disease (AD) and amyotrophic lateral sclerosis (ALS), yet …

OBJECTIVE—We determined whether reduced insulin sensitivity, mitochondrial dysfunction,
and other age-related dysfunctions are inevitable consequences of aging or secondary to …

Sirtuins are a family of NAD+-dependent protein deacetylases widely distributed in all phyla
of life. Accumulating evidence indicates that sirtuins are important regulators of organism life …

Background: Multi-drug-resistant bacteria such as Methicillin-Resistant Staphylococcus
aureus (MRSA) disseminate rapidly amongst patients in healthcare facilities and suppose …