[HTML][HTML] Lipocalin-2: Structure, function, distribution and role in metabolic disorders
S Al Jaberi, A Cohen, C D'Souza… - Biomedicine & …, 2021 - Elsevier
Abstract Lipocalin-2 (LCN-2) is a novel, 198 amino acid adipocytokine also referred to as
neutrophil gelatinase-associated lipocalin (NGAL). LCN-2 is a circulatory protein …
neutrophil gelatinase-associated lipocalin (NGAL). LCN-2 is a circulatory protein …
Cellular and molecular mechanisms of kidney fibrosis
Renal fibrosis is the final pathological process common to any ongoing, chronic kidney
injury or maladaptive repair. It is considered as the underlying pathological process of …
injury or maladaptive repair. It is considered as the underlying pathological process of …
Netting neutrophils induce endothelial damage, infiltrate tissues, and expose immunostimulatory molecules in systemic lupus erythematosus
E Villanueva, S Yalavarthi, CC Berthier… - The Journal of …, 2011 - journals.aai.org
An abnormal neutrophil subset has been identified in the PBMC fractions from lupus
patients. We have proposed that these low-density granulocytes (LDGs) play an important …
patients. We have proposed that these low-density granulocytes (LDGs) play an important …
Increased LCN2 (lipocalin 2) in the RPE decreases autophagy and activates inflammasome-ferroptosis processes in a mouse model of dry AMD
In dry age-related macular degeneration (AMD), LCN2 (lipocalin 2) is upregulated. Whereas
LCN2 has been implicated in AMD pathogenesis, the mechanism remains unknown. Here …
LCN2 has been implicated in AMD pathogenesis, the mechanism remains unknown. Here …
The multifaceted roles of neutrophil gelatinase associated lipocalin (NGAL) in inflammation and cancer
Neutrophil gelatinase associated lipocalin (NGAL), also known as oncogene 24p3,
uterocalin, siderocalin or lipocalin 2, is a 24kDa secreted glycoprotein originally purified …
uterocalin, siderocalin or lipocalin 2, is a 24kDa secreted glycoprotein originally purified …
The review of current knowledge on neutrophil gelatinase-associated lipocalin (NGAL)
K Romejko, M Markowska, S Niemczyk - International journal of molecular …, 2023 - mdpi.com
Neutrophil gelatinase-associated lipocalin (NGAL) is a 25-kDa protein that is secreted
mostly by immune cells such as neutrophils, macrophages, and dendritic cells. Its production …
mostly by immune cells such as neutrophils, macrophages, and dendritic cells. Its production …
Novel biomarkers in the diagnosis of chronic kidney disease and the prediction of its outcome
J Rysz, A Gluba-Brzózka, B Franczyk… - International journal of …, 2017 - mdpi.com
In its early stages, symptoms of chronic kidney disease (CKD) are usually not apparent.
Significant reduction of the kidney function is the first obvious sign of disease. If diagnosed …
Significant reduction of the kidney function is the first obvious sign of disease. If diagnosed …
[HTML][HTML] Biomarkers in chronic kidney disease, from kidney function to kidney damage
S Lopez-Giacoman, M Madero - World journal of nephrology, 2015 - ncbi.nlm.nih.gov
Chronic kidney disease (CKD) typically evolves over many years, with a long latent period
when the disease is clinically silent and therefore diagnosis, evaluation and treatment is …
when the disease is clinically silent and therefore diagnosis, evaluation and treatment is …
[HTML][HTML] Biomarkers in chronic kidney disease: a review
Chronic kidney disease (CKD) is a major public health problem. The classification of CKD by
KDOQI and KDIGO and the routine eGFR reporting have resulted in increased identification …
KDOQI and KDIGO and the routine eGFR reporting have resulted in increased identification …
Reactive astrocytes secrete lcn2 to promote neuron death
F Bi, C Huang, J Tong, G Qiu… - Proceedings of the …, 2013 - National Acad Sciences
Glial reaction is a common feature of neurodegenerative diseases. Recent studies have
suggested that reactive astrocytes gain neurotoxic properties, but exactly how reactive …
suggested that reactive astrocytes gain neurotoxic properties, but exactly how reactive …