Background: The G protein-coupled receptor 55 (GPR55) is a mammalian orphan receptor
that awaits a formal classification. There are an increasing number of reports directed to …

The cannabinoid system is ubiquitously present and is classically considered to engage in
neural and immunity processes. Yet, the role of the cannabinoid system in the whole body …

Cannabidiol (CBD), a major non-psychotropic cannabinoid found in the Cannabis plant, has
been shown to exert anti-nociceptive, anti-psychotic, and anti-convulsant effects and to also …

Cannabis use is associated with cardiovascular adverse effects ranging from arrhythmias to
sudden cardiac death. The exact mechanism of action behind these activities is unknown …

Introduction Synthetic cannabinoid receptor agonists (SCRAs) are heterogeneous
compounds originally intended as probes of the endogenous cannabinoid system or as …

Rationale Cardiovascular disease is now recognized as the number one cause of death in
the world, and the size of the population at risk continues to increase rapidly. The …

Sudden cardiac death (SCD) accounts for up to 450,000 deaths every year in the United
States (Zipes et al.(2006)). Most cases of sudden cardiac death occur in subjects with no …

Synthetic cannabinoids (SCBs) are widely used recreational substances especially among
adults. Although they have been considered as safe during the marketing process, our …

Cannabis use is associated with known cardiovascular side effects such as cardiac
arrhythmias or even sudden cardiac death. The mechanisms behind these adverse effects …

Background In the past couple of years, there has been an outbreak of synthetic
cannabinoid (SC) use in major cities in the United States. Patients can present with various …