Protein–protein interactions (PPIs) have pivotal roles in life processes. The studies showed
that aberrant PPIs are associated with various diseases, including cancer, infectious …

Abstract Purpose of Review Apoptosis is a major mechanism of cancer cell death. Thus,
evasion of apoptosis results in therapy resistance. Here, we review apoptosis modulators in …

Immunogenic cell death (ICD) is a form of regulated cell death (RCD) induced by various
stresses and produces antitumor immunity via damage-associated molecular patterns …

X-linked inhibitor of apoptosis protein (XIAP) is a member of inhibitor of apoptosis protein
(IAP) family responsible for neutralizing the caspases-3, caspases-7, and caspases-9 …

In recent years, proteolysis-targeting chimeras (PROTACs), capable of achieving targeted
protein degradation, have proven their great therapeutic potential and usefulness as …

Abstract Heat shock protein (HSP) 90, an important component of the molecular chaperone
network, is closely concerned with cellular signaling pathways and stress response by …

Simple Summary The Inhibitor of Apoptosis (IAP) family of proteins has emerged as a
potential pharmacological target in cancer. Abnormal expression of IAPs can lead to …

Apoptosis, an important form of programmed cell death (PCD), is a tightly regulated cellular
process to eliminate unwanted or damaged cells. Resistance of apoptosis is a hallmark of …